Matrilin-2 Antibody - BSA Free

Western Blot: Matrilin-2 Antibody [NBP1-76328] - Analysis of MATN2 in 3T3 cell lysate with MATN2 antibody at (A) 1 and (B) 2 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Matrilin-2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Matrilin-2 Antibody - BSA Free (NBP1-76328) is a polyclonal antibody validated for use in WB and ELISA. Anti-Matrilin-2 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human MATN2. The immunogen is located within amino acids 820 - 870 of MATN2. Amino Acid Squence: EALEDSDGRQDSPA
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MATN2
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1-2 ug/ml
• Theoretical MW: 105 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control Peptide:

  Matrilin-2 Peptide (NBP1-76328PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for Matrilin-2 Antibody - BSA Free

• MATN2
• matrilin 2
• Matrilin2
• Matrilin-2

Background

Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. The matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil alpha-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation and diseases such as astrocytoma and liver carcinoma. Recent studies show that MATN2 is a permissive substrate for axonal growth and cell migration, and it is required for successful nerve regeneration.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Matrilin-2 Antibody (NBP1-76328)(1)

Publication using NBP1-76328

• Zhang S, Zhang M, Huang H et al. High glucose-induced Matrilin-2 expression in mouse mesangial cells was mediated by transforming growth factor beta 1 (TGF-beta1). Biochem. Biophys. Res. Commun. 2016-04-20 [PMID: 27105914] (WB, Mouse)

Bioinformatics

• Gene Symbol: MATN2
• Uniprot:
  • NP_085072(Human)