MATK Antibody (9D7)

Images

 
Western Blot: MATK Antibody (9D7) [NBP1-47454] - Western blot analysis using anti-MATK mAb against K562 cell lysate (1).
Flow Cytometry: MATK Antibody (9D7) [NBP1-47454] - Flow cytometric analysis of K562 cells using anti-MATK mAb (green) and negative control (purple).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow
Clone
9D7
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

MATK Antibody (9D7) Summary

Immunogen
Purified recombinant fragment of human MATK expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MATK
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1: 500-1:2000
  • ELISA 1:10000
  • Flow Cytometry
Theoretical MW
56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
50% glycerol
Purity
Protein G purified

Alternate Names for MATK Antibody (9D7)

  • CHK
  • Csk-type protein tyrosine kinase
  • CTKEC 2.7.10.2
  • DKFZp434N1212
  • EC 2.7.10
  • Hematopoietic consensus tyrosine-lacking kinase
  • HHYLTK
  • hydroxyaryl-protein kinase
  • HYL tyrosine kinase
  • HYLCsk-homologous kinase
  • HYLTK
  • leukocyte carboxyl-terminal src kinase related
  • Lsk
  • megakaryocyte-associated tyrosine kinase
  • megakaryocyte-associated tyrosine-protein kinase
  • MGC1708
  • MGC2101
  • Protein kinase HYL
  • tyrosine kinase MATK
  • Tyrosine-protein kinase CTK
  • tyrosylprotein kinase

Background

megakaryocyte-associated tyrosine kinase. The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MATK