MALT1 Antibody (SPM578) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC-Fr, IHC-P, IP
Clone
SPM578
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

MALT1 Antibody (SPM578) [DyLight 405] Summary

Immunogen
Human MALT1 recombinant fragment (aa701-808)
Localization
Cytoplasmic
Marker
MALT-Lymphoma Marker
Specificity
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MALT1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA 1-5ug/ml for coating
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MALT1 Antibody (SPM578) [DyLight 405]

  • caspase-like protein
  • DKFZp434L132
  • EC 3.4.22.-
  • MALT associated translocation
  • MALT lymphoma-associated translocation
  • MALT1
  • MLT1
  • MLTMALT-lymphoma associated translocation
  • mucosa associated lymphoid tissue lymphoma translocation gene 1
  • mucosa-associated lymphoid tissue lymphoma translocation protein 1
  • Paracaspase

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for MALT1 Antibody (NBP2-34811V) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 NBP2-34811AF405
Alexa Fluor 488 NBP2-34811AF488
Alexa Fluor 647 NBP2-34811AF647
Alexa Fluor 700 NBP2-34811AF700
Allophycocyanin NBP2-34811APC
Biotin NBP2-34811B
DyLight 350 NBP2-34811UV
DyLight 405 NBP2-34811V
DyLight 488 NBP2-34811G
DyLight 550 NBP2-34811R
DyLight 650 NBP2-34811C
DyLight 680 NBP2-34811FR
DyLight 755 NBP2-34811IR
HRP NBP2-34811H
Janelia Fluor 549 NBP2-34811JF549
Janelia Fluor 646 NBP2-34811JF646
PE NBP2-34811PE
PerCP NBP2-34811PCP

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Bioinformatics Tool for MALT1 Antibody (NBP2-34811V)

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Bioinformatics

Gene Symbol MALT1