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MALT1 Antibody (SPM578) [Alexa Fluor® 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC-Fr, IHC-P, IP
Clone
SPM578
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 488
NBP2-34811AF488
Alexa Fluor 647
NBP2-34811AF647
Alexa Fluor 700
NBP2-34811AF700
Allophycocyanin
NBP2-34811APC
Biotin
NBP2-34811B
DyLight 350
NBP2-34811UV
DyLight 405
NBP2-34811V
DyLight 488
NBP2-34811G
DyLight 550
NBP2-34811R
DyLight 650
NBP2-34811C
DyLight 680
NBP2-34811FR
DyLight 755
NBP2-34811IR
HRP
NBP2-34811H
PE
NBP2-34811PE
PerCP
NBP2-34811PCP
Unconjugated
NBP2-32872-0.1mg
View Available Formulations
Catalog# & Formulation Size Price
IHC-Prediluted
NBP2-44349
Azide and BSA Free
NBP2-34811-0.2 mg
Azide and BSA Free
NBP2-34811-0.1 mg
Standard Formulation
NBP2-32872-0.1mg
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MALT1 Antibody (SPM578) [Alexa Fluor® 405] Summary

Immunogen
Human MALT1 recombinant fragment (aa701-808)
Localization
Cytoplasmic
Marker
MALT-Lymphoma Marker
Specificity
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MALT1
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA 1-5ug/ml for coating
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
Application Notes
Immunohistochemistry (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Theoretical MW
93 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for MALT1 Antibody (SPM578) [Alexa Fluor® 405]

  • caspase-like protein
  • DKFZp434L132
  • EC 3.4.22.-
  • MALT associated translocation
  • MALT lymphoma-associated translocation
  • MALT1
  • MLT1
  • MLTMALT-lymphoma associated translocation
  • mucosa associated lymphoid tissue lymphoma translocation gene 1
  • mucosa-associated lymphoid tissue lymphoma translocation protein 1
  • Paracaspase

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NB100-56715
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MALT1 Antibody
(SPM578) [Alexa Fluor ...
NBP2-34811AF405
MALT1 Antibody (SPM578) [Alexa Fluor® 405]
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC-Fr, IHC-P, IP

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MALT1
Entrez
Uniprot

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