MALT1 Products

Antibodies
MALT1 Antibody
MALT1 Antibody
NB100-56158
Species: Hu
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
MALT1 Antibody (MALT1-C)
MALT1 Antibody (MALT1-C)
MAB4850
Species: Hu
Applications: WB, Simple Western
Host: Mouse Monoclonal
Antibody Pairs
MALT1 Antibody Pair
MALT1 Antibody Pair
H00010892-PW1
Species: Hu
Applications: WB, IP
MALT1 Antibody Pair
MALT1 Antibody Pair
H00010892-AP21
Species: Hu
Applications: S-ELISA
Lysates
MALT1 Overexpression Lysate ( ...
MALT1 Overexpression Lysate (Native)
NBP2-05067
Applications: WB
MALT1 Overexpression Lysate ( ...
MALT1 Overexpression Lysate (Native)
NBL1-12832
Applications: WB
MALT1 Overexpression Lysate ( ...
MALT1 Overexpression Lysate (Denat...
H00010892-T01
Applications: WB
Proteins
MALT1 Recombinant Protein
MALT1 Recombinant Protein
H00010892-P01
Species: Hu
Applications: WB, ELISA, PA
MALT1 Partial Recombinant Pro ...
MALT1 Partial Recombinant Protein
H00010892-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
MALT1 RNAi
MALT1 RNAi
H00010892-R01
Species: Hu
MALT1 RNAi
MALT1 RNAi
H00010892-R02
Species: Hu

Description

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), also known as MLT1 or paracaspase 1, is a member of the human paracaspase family and an interacting partner of B-cell lymphoma 10 (Bcl-10) (1). In vitro, In vitro, MALT1 synergizes with BCL10 to enhance nuclear factor B activation (2) and to mediate IB kinase (IKK) activation by facilitating the ubiquitinylation of the NF-B essential modulator (NEMO) (3). MALT1 is found in recurrent chromosomal translocations in non-Hodgkin B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT). One common translocation juxtaposes the MALT1 gene to the IgH promoter region, resulting in up-regulation of Bcl-10 and MALT1 (4). Another common translocation creates a fusion between MALT1 and the inhibitor of apoptosis gene API2 (cIAP2/HIAP1) (5).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 10892
Alternate Names
  • Paracaspase
  • caspase-like protein
  • EC 3.4.22.-
  • MLT1
  • paracaspase
  • DKFZp434L132
  • mucosa-associated lymphoid tissue lymphoma translocation protein 1
  • MALT lymphoma-associated translocation
  • MLTMALT-lymphoma associated translocation
  • MALT associated translocation
  • mucosa associated lymphoid tissue lymphoma translocation gene 1

Research Areas for MALT1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Tumor Suppressors

Bioinformatics Tool for MALT1

Discover related pathways, diseases and genes to MALT1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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