MALT1 Antibody (MT1/410) [Allophycocyanin]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-33054APC
    • Availability
      Product Discontinued

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MALT1 Antibody (MT1/410) [Allophycocyanin] Summary

Immunogen
Human MALT1 recombinant fragment (aa701-808)
Localization
Cytoplasmic
Marker
MALT-Lymphoma Marker
Specificity
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MALT1
Purity
Protein G purified
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Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MALT1 Antibody (MT1/410) [Allophycocyanin]

  • caspase-like protein
  • DKFZp434L132
  • EC 3.4.22.-
  • MALT associated translocation
  • MALT lymphoma-associated translocation
  • MALT1
  • MLT1
  • MLTMALT-lymphoma associated translocation
  • mucosa associated lymphoid tissue lymphoma translocation gene 1
  • mucosa-associated lymphoid tissue lymphoma translocation protein 1
  • Paracaspase

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MALT1
Entrez