Mouse IgG1 Isotype Control (11711) [Allophycocyanin]

Human peripheral blood monocytes were stained with Mouse Anti-Human LILRA6/CD85b APC-conjugated Monoclonal Antibody (Catalog # FAB8656A, filled histogram) or Mouse IgG Isotype Control Antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Mu
• Applications: Ctrl
• Clone: 11711
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

Mouse IgG1 Isotype Control (11711) [Allophycocyanin] Summary

• Immunogen: KLH
• Specificity: Selected for use as mouse IgG₁ isotype control for flow cytometry applications.
• Source: N/A
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: IGHG1
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Control 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IgG1 Isotype Control (11711) [Allophycocyanin]

• IgG1
• Igh-4
• RGD1359539
• VH7183

Background

R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.

Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Isotype Controls are guaranteed for 1 year from date of receipt.

Publications for IgG1 Isotype Control (IC002A)(45)

Publications using IC002A

• Jia, H;Moore, M;Wadhwa, M;Burns, C; Human iPSC-Derived Endothelial Cells Exhibit Reduced Immunogenicity in Comparison With Human Primary Endothelial Cells Stem cells international 2024-12-09 [PMID: 39687754] (Flow Cytometry Control, Human)
• Bisson, JA;Gordillo, M;Kumar, R;de Silva, N;Yang, E;Banks, KM;Shi, ZD;Lee, K;Yang, D;Chung, WK;Huangfu, D;Evans, T; GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis bioRxiv : the preprint server for biology 2024-07-11 [PMID: 39026742] (Flow Cytometry Control, Human)
• J Kleemann, K Steinhorst, V König, N Zöller, J Cinatl, D Özistanbul, R Kaufmann, M Meissner, S Kippenberg Functional Downregulation of PD-L1 and PD-L2 by CpG and non-CpG Oligonucleotides in Melanoma Cells Cancers, 2022-09-27;14(19):. 2022-09-27 [PMID: 36230620] (Flow Cytometry, Human)
• R Yoshida, M Saigi, T Tani, BF Springer, H Shibata, S Kitajima, NR Mahadevan, M Campisi, W Kim, Y Kobayashi, TC Thai, K Haratani, Y Yamamoto, SK Sundararam, EH Knelson, A Vajdi, I Canadas, R Uppaluri, CP Paweletz, JJ Miret, PH Lizotte, PC Gokhale, PA Janne, DA Barbie MET-induced CD73 restrains STING-mediated immunogenicity of EGFR-mutant lung cancer Cancer Research, 2022-11-02;0(0):. 2022-11-02 [PMID: 36066413] (Flow Cytometry Control, Human)
• Linda Hofmann, Valentin Medyany, Jasmin Ezić, Ramin Lotfi, Beate Niesler, Ralph Röth et al. Cargo and Functional Profile of Saliva-Derived Exosomes Reveal Biomarkers Specific for Head and Neck Cancer Frontiers in Medicine 2022-07-11 [PMID: 35899209] (Flow Cytometry Control, Human)
• Sofie Hagelund, Anna Trauzold Impact of Extracellular pH on Apoptotic and Non-Apoptotic TRAIL-Induced Signaling in Pancreatic Ductal Adenocarcinoma Cells Frontiers in Cell and Developmental Biology 2022-02-24 [PMID: 35281089]
• Hai-Bo Huang, Hai-Tao Luo, Na-Na Wei, Miao-Ling Liu, Fei He, Wei Yang et al. Integrative analysis reveals a lineage-specific circular RNA landscape for adipo-osteogenesis of human mesenchymal stem cells Stem Cell Research & Therapy 2022-03-12 [PMID: 35279206] (Flow Cytometry, Human)
• Miriam Gaggianesi, Laura Rosa Mangiapane, Chiara Modica, Vincenzo Davide Pantina, Gaetana Porcelli, Simone Di Franco et al. Dual Inhibition of Myc Transcription and PI3K Activity Effectively Targets Colorectal Cancer Stem Cells Cancers (Basel) 2022-01-28 [PMID: 35158939]
• Richard E. Beatson, Ana C. Parente-Pereira, Leena Halim, Domenico Cozzetto, Caroline Hull, Lynsey M. Whilding et al. TGF-beta 1 potentiates V gamma 9Vδ2 T cell adoptive immunotherapy of cancer Cell Reports Medicine 2021-12-21 [PMID: 35028614]
• Stephane Oudard, Nadine Benhamouda, Bernard Escudier, Patrice Ravel, Thi Tran, Emeline Levionnois et al. Decrease of Pro-Angiogenic Monocytes Predicts Clinical Response to Anti-Angiogenic Treatment in Patients with Metastatic Renal Cell Carcinoma Cells 2021-12-22 [PMID: 35011579]
• MN Theodoraki, S Laban, EK Jackson, R Lotfi, PJ Schuler, C Brunner, TK Hoffmann, TL Whiteside, L Hofmann Changes in circulating exosome molecular profiles following surgery/(chemo)radiotherapy: early detection of response in head and neck cancer patients British Journal of Cancer, 2021-10-12;0(0):. 10/12/2021 [PMID: 34642463]
• A Turdo, A Glaviano, G Pepe, F Calapà, S Raimondo, ME Fiori, D Carbone, MG Basilicata, V Di Sarno, C Ostacolo, B Parrino, S Cascioferr, C Pecoraro, S Di Franco, D Bellavia, M Gaggianesi, V Veschi, M Lo Iacono, G Ganduscio, VD Pantina, LR Mangiapane, MR Bongiorno, R Alessandro, M Todaro, R De Maria, P Diana, P Campiglia, G Stassi Nobiletin and Xanthohumol Sensitize Colorectal Cancer Stem Cells to Standard Chemotherapy Cancers, 2021-08-04;13(16):. 2021-08-04 [PMID: 34439086] (Flow Cytometry, Human)
• Simone Di Franco, Barbara Parrino, Miriam Gaggianesi, Vincenzo Davide Pantina, Paola Bianca, Annalisa Nicotra et al. CHK1 inhibitor sensitizes resistant colorectal cancer stem cells to nortopsentin iScience 2021-06-25 [PMID: 34169240] (Flow Cytometry Control, Human)
• Soraia Fernandes, Tamara Fernandez, Sabrina Metze, Preethi B. Balakrishnan, Binh T. Mai, John Conteh et al. Magnetic Nanoparticle-Based Hyperthermia Mediates Drug Delivery and Impairs the Tumorigenic Capacity of Quiescent Colorectal Cancer Stem Cells ACS Applied Materials & Interfaces 2021-04-14 [PMID: 33797220]
• LA Ricaurte-C, A Lovera, DA Moreno-Pér, MD Bohórquez, CF Suárez, E Gutiérrez-, L Cuy-Chapar, D Garzón-Osp, MA Patarroyo Two 20-Residue-Long Peptides Derived from Plasmodium vivax Merozoite Surface Protein 10 EGF-Like Domains Are Involved in Binding to Human Reticulocytes International Journal of Molecular Sciences, 2021-02-05;22(4):. 2021-02-05 [PMID: 33562650] (Flow Cytometry, Human)
• CAA Lee, P Banerjee, BJ Wilson, S Wu, Q Guo, G Berg, S Karpova, A Mishra, JW Lian, J Tran, M Emmerich, GF Murphy, MH Frank, NY Frank Targeting the ABC transporter ABCB5 sensitizes glioblastoma to temozolomide-induced apoptosis through a cell-cycle checkpoint regulation mechanism J. Biol. Chem., 2020-04-20;0(0):. 2020-04-20 [PMID: 32317280] (Flow Cytometry, Mouse)
• S Fujiyama, N Hori, T Sato, S Enosawa, M Murata, E Kobayashi Development of an ex vivo xenogeneic bone environment producing human platelet-like cells PLoS ONE, 2020-04-07;15(4):e0230507. 2020-04-07 [PMID: 32255777] (Flow Cytometry, Human)
• Elena Stocco, Silvia Barbon, Monica Piccione, Elisa Belluzzi, Lucia Petrelli, Assunta Pozzuoli et al. Infrapatellar Fat Pad Stem Cells Responsiveness to Microenvironment in Osteoarthritis: From Morphology to Function Frontiers in Cell and Developmental Biology 2019-12-10 [PMID: 31921840]
• Y Abe, M Chiba, S Yaklai, RS Pechayco, H Suzuki, T Takahashi Increase in bone metabolic markers and circulating osteoblast-lineage cells after orthognathic surgery Sci Rep, 2019-12-27;9(1):20106. 2019-12-27 [PMID: 31882726] (Flow Cytometry, Human)
• W Nowak, LN Grendas, LM Sanmarco, IG Estecho, ÁR Arena, N Eberhardt, DE Rodante, MP Aoki, FM Daray, EA Carrera Si, AE Errasti Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTOR EBioMedicine, 2019-11-18;0(0):. 2019-11-18 [PMID: 31753725] (ICC, Human)
• Jason T. Blackard, Ling Kong, Susan D. Rouster, Rebekah Karns, Paul S. Horn, Shyam Kottilil et al. CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro PLOS ONE 2019-10-29 [PMID: 31661521]
• V Veschi, LR Mangiapane, A Nicotra, S Di Franco, E Scavo, T Apuzzo, DS Sardina, M Fiori, A Benfante, ML Colorito, G Cocorullo, F Giuliante, C Cipolla, G Pistone, MR Bongiorno, A Rizzo, CM Tate, X Wu, S Rowlinson, LF Stancato, M Todaro, R De Maria, G Stassi Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant Oncogene, 2019-10-07;0(0):. 2019-10-07 [PMID: 31591478] (ICC, Human)
• U Mert, A Adawy, E Scharff, P Teichmann, A Willms, V Haselmann, C Colmorgen, J Lemke, S von Karste, J Fritsch, A Trauzold TRAIL Induces Nuclear Translocation and Chromatin Localization of TRAIL Death Receptors Cancers (Basel), 2019-08-14;11(8):. 2019-08-14 [PMID: 31416165] (Flow Cytometry, Human)
• Erna-Zulaikha Dayang, Josée Plantinga, Bram ter Ellen, Matijs van Meurs, Grietje Molema, Jill Moser Identification of LPS-Activated Endothelial Subpopulations With Distinct Inflammatory Phenotypes and Regulatory Signaling Mechanisms Frontiers in Immunology 2019-05-24 [PMID: 31178871]
• A Willms, H Schittek, S Rahn, J Sosna, U Mert, D Adam, A Trauzold Impact of p53 status on TRAIL-mediated apoptotic and non-apoptotic signaling in cancer cells PLoS ONE, 2019-04-04;14(4):e0214847. 2019-04-04 [PMID: 30947287] (Flow Cytometry, Human)
• FJ Zapatero-B, E Dietzel, O Dolnik, K Döhner, R Costa, B Hertel, B Veselkova, J Kirui, A Klintworth, MP Manns, S Pöhlmann, T Pietschman, T Krey, S Ciesek, G Gerold, B Sodeik, S Becker, T von Hahn Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors Viruses, 2019-03-19;11(3):. 3/19/2019 [PMID: 30893855]
• T Colunga, M Hayworth, S Kre beta , DM Reynolds, L Chen, KL Nazor, J Baur, AM Singh, JF Loring, M Metzger, S Dalton Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair Cell Rep, 2019-03-05;26(10):2566-2579.e10. 3/5/2019 [PMID: 30840882]
• W Li, A Dick, F Lu, H Zhang, H Sun Induction of MET Receptor Tyrosine Kinase Down-regulation through Antibody-mediated Receptor Clustering Sci Rep, 2019-02-13;9(1):1988. 2019-02-13 [PMID: 30760737] (ICC, Human)
• MJ Moreno, A Gallardo, S Novelli, A Mozos, M Aragó, MÁ Pavón, MV Céspedes, V Pallarès, A Falgàs, M Alcoceba, O Blanco, M Gonzalez-D, J Sierra, R Mangues, I Casanova CXCR7 expression in diffuse large B-cell lymphoma identifies a subgroup of CXCR4+ patients with good prognosis PLoS ONE, 2018-06-19;13(6):e0198789. 2018-06-19 [PMID: 29920526] (Flow Cytometry, Human)
• WJ Zacharias, DB Frank, JA Zepp, MP Morley, FA Alkhaleel, J Kong, S Zhou, E Cantu, EE Morrisey Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor Nature, 2018-02-28;555(7695):251-255. 2018-02-28 [PMID: 29489752] (Control, Human)
• H Zhang, J Wang, L Wang, H Xie, L Chen, S He Role of IL-18 in atopic asthma is determined by balance of IL-18/IL-18BP/IL-18R J. Cell. Mol. Med., 2017-09-18;0(0):. 2017-09-18 [PMID: 28922563] (Flow Cytometry Control)
• Amardeep Singh, Yousif Subhi, Marie Krogh Nielsen, Mads Krüger Falk, Sara Maj Hyldig Matzen, Finn Sellebjerg et al. Systemic frequencies of T helper 1 and T helper 17 cells in patients with age-related macular degeneration: A case-control study Scientific Reports 2017-04-04 [PMID: 28377586]
• CL Esteves, TA Sheldrake, L Dawson, T Menghini, E Rink, K Amilon, N Khan, B Peault, X Donadeu Equine Mesenchymal Stromal Cells retain a pericyte-like phenotype Stem Cells Dev., 2017-05-09;0(0):. 2017-05-09 [PMID: 28376684] (Flow Cytometry, Equine)
• H Schwarz, J Gornicec, T Neuper, MA Parigiani, M Wallner, A Duschl, J Horejs-Hoe Biological Activity of Masked Endotoxin Sci Rep, 2017-03-20;7(0):44750. 2017-03-20 [PMID: 28317862] (Flow Cytometry Control, Human)
• N Asada, Y Kunisaki, H Pierce, Z Wang, NF Fernandez, A Birbrair, A Ma'ayan, PS Frenette Differential cytokine contributions of perivascular haematopoietic stem cell niches Nat. Cell Biol, 2017-02-20;19(3):214-223. 2017-02-20 [PMID: 28218906] (Flow Cytometry, Mouse)
• Tingting Cheng, Kui Zhai, Yan Chang, Guidong Yao, Jiahuan He, Fang Wang et al. CHIR99021 combined with retinoic acid promotes the differentiation of primordial germ cells from human embryonic stem cells Oncotarget 2017-01-31 [PMID: 27999196]
• Sabine Stindt, Patricia Cebula, Ute Albrecht, Verena Keitel, Jan Schulte am Esch, Wolfram T. Knoefel et al. Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family PLOS ONE 2016-02-17 [PMID: 26886748]
• Maier E, Mittermeir M, Ess S, Neuper T, Schmiedlechner A, Duschl A, Horejs-Hoeck J Prerequisites for Functional Interleukin 31 Signaling and Its Feedback Regulation by Suppressor of Cytokine Signaling 3 (SOCS3). J Biol Chem, 2015-08-25;290(41):24747-59. 2015-08-25 [PMID: 26306032] (Flow Cytometry, Human)
• Qingyu Zhang, Caijie Lu, Tao Fang, Yongcun Wang, Wenhua Hu, Jie Qiao et al. Notch3 functions as a regulator of cell self-renewal by interacting with the beta -catenin pathway in hepatocellular carcinoma Oncotarget 2015-02-28 [PMID: 25668819]
• Merkely B, Gara E, Lendvai Z, Skopal J, Leja T, Zhou W, Kosztin A, Varady G, Mioulane M, Bagyura Z, Nemeth T, Harding S, Foldes G Signaling via PI3K/FOXO1A pathway modulates formation and survival of human embryonic stem cell-derived endothelial cells. Stem Cells Dev, 2014-12-22;24(7):869-78. 2014-12-22 [PMID: 25387407] (Flow Cytometry, Human)
• Hashimoto , Noriaki, Tsunedomi , Ryouichi, Yoshimura , Kiyoshi, Watanabe , Yusaku, Hazama , Shoichi, Oka , Masaaki Cancer stem-like sphere cells induced from de-differentiated hepatocellular carcinoma-derived cell lines possess the resistance to anti-cancer drugs. BMC Cancer, 2014-09-27;14(0):722. 2014-09-27 [PMID: 25260650] (Flow Cytometry Control, Human)
• Hoellenriegel J, Zboralski D, Maasch C, Rosin N, Wierda W, Keating M, Kruschinski A, Burger J The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization. Blood, 2013-11-25;123(7):1032-9. 2013-11-25 [PMID: 24277076] (Flow Cytometry, Mouse)
• Takashi Angata, Takeo Ishii, Takashi Motegi, Ritsuko Oka, Rachel E. Taylor, Paula Campos Soto et al. Loss of Siglec-14 reduces the risk of chronic obstructive pulmonary disease exacerbation Cellular and Molecular Life Sciences 2013-09-01 [PMID: 23519826]
• Vroling L, Yuana Y, Schuurhuis GJ, van Hinsbergh VW, Gundy C, de Haas R, van Cruijsen H, Boven E, Hoekman K, Broxterman HJ VEGFR2 expressing circulating (progenitor) cell populations in volunteers and cancer patients. Thromb. Haemost., 2007-08-01;98(2):440-50. 2007-08-01 [PMID: 17721629] (Control, Human)
• Li Y, Fan J, Chen M, Li W, Woodley DT Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migration. J. Invest. Dermatol., 2006-05-11;126(9):2096-105. 2006-05-11 [PMID: 16691197] (Control, Human)

Reviews for IgG1 Isotype Control (IC002A) (2)

Average Rating: 5

(Based on 2 reviews)

reviewed by: Verified Customer 02/06/2018

Summary

• Lot: LBN1216101

reviewed by: Verified Customer 10/23/2017

Summary

• Lot: LBN1216101

Bioinformatics

• Gene Symbol: IGHG1