MAGP-2/MFAP5 Antibody [Allophycocyanin]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Allophycocyanin

MAGP-2/MFAP5 Antibody [Allophycocyanin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human MAGP-2/MFAP5
  Ile22-Leu173
  Accession # Q13361
• Specificity: Detects human MAGP-2/MFAP5 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human MAGP-1 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: MFAP5
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for MAGP-2/MFAP5 Antibody [Allophycocyanin]

• MAGP2
• MAGP-2
• MAGP2MFAP-5
• MFAP5
• Microfibril-associated glycoprotein 2
• microfibrillar associated protein 5
• microfibrillar-associated protein 5
• MP25
• MP25microfibril-associated glycoprotein-2

Background

MFAP5, also known as Microfibrillar-associated protein 5, is a 173 amino acid protein that is 20 kDa, extracellular matrix secreted, and it is a component of the elastin-associated microfibrils. Current research is being performed on this protein involvement in marfan syndrome, scleroderma and skin fibrosis. The protein is involved in molecules associated with elastic fibres, extracellular matrix organization, elastic fibre formation, tropoelastin associates with microfibrils, elastin cross-linking by lysyl oxidase, and notch signaling pathways where it interacts with FBN2, JAG1, JAG2, MEGF6, VWF, FBLN1, FBN1, GYG1, DLL1, MFAP2, NOTCH1, ENAM, FBN3, and DLL4 proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MFAP5