Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody [FITC]

Images

 
There are currently no images for Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, Mu, Rt, PmSpecies Glossary
Applications ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
FITC

Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody [FITC] Summary

Immunogen
A genomic peptide made to an internal region of the human JMJD1A protein (within residues 250-400). [Swiss-Prot Q9Y4C1]
Localization
Nuclear in round spermatids. When spermatids start to elongate, JMJD1A localizes to the cytoplasm where it forms distinct foci which disappear in mature spermatozoa.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KDM3A
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
This JMJD1A antibody is useful for immunohistochemistry on paraffin tissues, immunocytochemistry/immunofluorescence and Western blot where a band is seen ~147 kDa. In ICC/IF, nuclear signal was observed in MCF-7 cells. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

Reactivity Notes

Human, mouse and primate. Rat reactivity reported in scientific literature (PMID: 27807143).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody [FITC]

  • EC 1.14.11
  • EC 1.14.11.-
  • JHDM2A
  • JHDM2AJMJD1AJHMD2A
  • JmjC domain-containing histone demethylation protein 2A
  • JMJD1
  • JMJD1A
  • jumonji C domain-containing histone demethylase 2A
  • jumonji domain containing 1
  • jumonji domain containing 1A
  • Jumonji domain-containing protein 1A
  • KDM3A
  • KIAA0742
  • KIAA0742DKFZp686A24246
  • Lysine (K)specific Demethylase 3A
  • Lysine (K)-specific Demethylase 3A
  • lysine-specific demethylase 3A
  • testis-specific protein A
  • TSGA
  • TSGADKFZp686P07111

Background

JMJD1A is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. It preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. JMJD1A is involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. It's also Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 which are required for packaging and condensation of sperm chromatin. Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB500-171
Species: Hu, Mu, Rt, Xp, Ye
Applications: WB, ChIP, ICC/IF, IHC, IHC-P
NB100-105
Species: Hu, Mu, Rt, Po, Bv, Ft, Mk, Pm, Rb, Sh, Xp, Ye
Applications: WB, ChIP, ELISA, Flow, GS, ICC/IF, IHC, IHC-Fr, IHC-P, IP, PLA, TCS, KO, LA
NBP1-49600
Species: Hu, Mu
Applications: WB, Simple Western, ChIP, ICC/IF, IHC, IHC-P
NBP2-30949
Species: Hu
Applications: IHC, IHC-P
NB100-1762
Species: Hu, Mu, Pm
Applications: WB, Simple Western, ChIP, ELISA, IHC, IHC-P
NB100-74605
Species: Hu, Mu
Applications: WB, IP
NB100-2379
Species: Hu, Mu, Rt, Pm
Applications: WB, Flow, ICC/IF
NB100-81657
Species: Hu, Mu
Applications: WB, IHC-P, IP
NB100-56603
Species: Hu, Pm
Applications: WB, IHC, IHC-P
NBP1-77072
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NB110-40585
Species: Hu, Mu
Applications: WB, ChIP, ICC/IF, IP
NB300-537
Species: Hu, Mu, Rt, Bv, Rb
Applications: WB, ChIP, Flow, GS, ICC/IF, IHC, IHC-P, IP
PP-A8620A-00
Species: Hu, Mu
Applications: WB, IHC, IP, DirELISA
NBP2-30567
Species: Hu
Applications: IHC, IHC-P
NB100-381
Species: Hu
Applications: WB, ChIP, IP, PLA
NBP1-89843
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NB200-310
Species: Hu, Mu, Rt, Mk
Applications: WB, ChIP, IP, IF
NBP1-76276
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P

Publications for Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F) (0)

There are no publications for Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F) (0)

There are no reviews for Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Products

Bioinformatics Tool for Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F)

Discover related pathways, diseases and genes to Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F)

Discover more about diseases related to Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F).
 

Pathways for Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F)

View related products by pathway.

PTMs for Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F)

Learn more about PTMs related to Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F).
 

Research Areas for Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody (NBP1-49601F)

Find related products by research area.

Blogs on Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A

There are no specific blogs for Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Lysine (K)-specific Demethylase 3A/KDM3A/JMJD1A Antibody [FITC] and receive a gift card or discount.

Bioinformatics

Gene Symbol KDM3A
Entrez