Human GDF-15 Quantikine ELISA Kit

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Catalog# & Conjugate Size Price

Human GDF-15 Quantikine ELISA Kit Summary

Background
The Quantikine Human GDF-15 immunoassay is a 3.5 hour solid phase ELISA designed to measure GDF-15 in cell culture supernates, serum, plasma, and urine. It contains CHO cell-expressed recombinant human GDF-15 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural GDF-15 showed linear curves that were parallel to the standard curves obtained using t...he Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of naturally occurring GDF-15.
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Specificity
Natural and recombinant human GDF-15
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
GDF15

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DGD150.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human GDF-15 Quantikine ELISA Kit

  • GDF15
  • GDF-15
  • growth differentiation factor 15
  • growth/differentiation factor 15
  • Macrophage inhibitory cytokine 1
  • MIC-1
  • MIC-1NSAID-activated gene 1 protein
  • MIC1Prostate differentiation factor
  • NAG-1
  • NAG-1NSAID-regulated gene 1 protein
  • NSAID (nonsteroidal inflammatory drug)-activated protein 1
  • PDF
  • PDFGDF-15
  • PLAB
  • PLABNRG-1
  • Placental bone morphogenetic protein
  • Placental TGF-beta
  • PTGF-beta
  • PTGFBPTGF-beta

Background

Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and -9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for GDF-15 (DGD150)(41)

We have publications tested in 2 confirmed species: Human, Rat.


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Human
(40)
Rat
(1)
All Species
Showing Publications 1 - 10 of 41. Show All 41 Publications.
Publications using DGD150 Applications Species
T Borner, HS Wald, MY Ghidewon, B Zhang, Z Wu, BC De Jonghe, D Breen, HJ Grill GDF15 Induces an Aversive Visceral Malaise State that Drives Anorexia and Weight Loss Cell Rep, 2020;31(3):107543. 2020 [PMID: 32320650] (Rat) Rat
VT Mitic, DR Stojanovic, MZ Deljanin I, MM Stojanovic, DB Petrovic, AM Ignjatovic, NZ Stefanovic, GM Kocic, VV Bojanic Cardiac Remodeling Biomarkers as Potential Circulating Markers of Left Ventricular Hypertrophy in Heart Failure with Preserved Ejection Fraction Tohoku J. Exp. Med., 2020;250(4):233-242. 2020 [PMID: 32295985] (Human) Human
DF De Jesus, K Orime, D Kaminska, T Kimura, G Basile, CH Wang, L Haertle, R Riemens, NK Brown, J Hu, V Männistö, AM Silva, E Dirice, YH Tseng, T Haaf, J Pihlajamäk, RN Kulkarni Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice J. Clin. Invest., 2020;0(0):. 2020 [PMID: 32250344] (Human) Human
Y Kagiyama, S Yatsuga, M Kinoshita, Y Koteda, S Kishimoto, Y Koga, K Suda Growth differentiation factor 15 as a useful biomarker of heart failure in young patients with unrepaired congenital heart disease of left to right shunt J Cardiol, 2019;0(0):. 2019 [PMID: 31883956] (Human) Human
N Noren Hoot, MH McFarland, DW Freeman, NA Mode, N Ezike, AB Zonderman, MK Evans Association of Extracellular Vesicle Protein Cargo with Race and Clinical Markers of Mortality Sci Rep, 2019;9(1):17582. 2019 [PMID: 31772226] (Human) Human
T Nakajima, I Shibasaki, T Sawaguchi, A Haruyama, H Kaneda, T Nakajima, T Hasegawa, T Arikawa, S Obi, M Sakuma, H Ogawa, S Toyoda, F Nakamura, S Abe, H Fukuda, T Inoue Growth Differentiation Factor-15 (GDF-15) is a Biomarker of Muscle Wasting and Renal Dysfunction in Preoperative Cardiovascular Surgery Patients J Clin Med, 2019;8(10):. 2019 [PMID: 31581569] (Human) Human
B Richter, T Uray, KA Krychtiuk, C Schriefl, M Lenz, A Nürnberger, SP Kastl, J Wojta, G Heinz, M Schwameis, WS Speidl Growth differentiation factor-15 predicts poor survival after cardiac arrest Resuscitation, 2019;143(0):22-28. 2019 [PMID: 31394153] (Human) Human
A Miyauchi, T Kouga, EF Jimbo, T Matsuhashi, T Abe, T Yamagata, H Osaka Apomorphine rescues reactive oxygen species-induced apoptosis of fibroblasts with mitochondrial disease Mitochondrion, 2019;0(0):. 2019 [PMID: 31356884] (Human) Human
L Traeger, I Ellermann, H Wiethoff, J Ihbe, I Gallitz, M Eveslage, R Moritz, E Herrmann, AJ Schrader, AU Steinbicke Serum Hepcidin and GDF-15 levels as prognostic markers in urothelial carcinoma of the upper urinary tract and renal cell carcinoma BMC Cancer, 2019;19(1):74. 2019 [PMID: 30646851] (Human) Human
H Engerud, K Hope, HF Berg, KE Fasmer, IL Tangen, IS Haldorsen, J Trovik, C Krakstad Plasma growth differentiation factor-15 is an independent marker for aggressive disease in endometrial cancer PLoS ONE, 2019;14(1):e0210585. 2019 [PMID: 30645608] (Human) Human
Show All 41 Publications.

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Product General Protocols

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FAQs for GDF-15 (DGD150). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

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Bioinformatics

Gene Symbol GDF15