Human GDF-15 Quantikine ELISA Kit

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Reactivity HuSpecies Glossary
Applications ELISA

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Human GDF-15 Quantikine ELISA Kit Summary

The Quantikine Human GDF-15 immunoassay is a 3.5 hour solid phase ELISA designed to measure GDF-15 in cell culture supernates, serum, plasma, and urine. It contains CHO cell-expressed recombinant human GDF-15 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural GDF-15 showed linear curves that were parallel to the standard curves obtained using t...he Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of naturally occurring GDF-15.
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Natural and recombinant human GDF-15
Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DGD150.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human GDF-15 Quantikine ELISA Kit

  • GDF15
  • GDF-15
  • growth differentiation factor 15
  • growth/differentiation factor 15
  • Macrophage inhibitory cytokine 1
  • MIC-1
  • MIC-1NSAID-activated gene 1 protein
  • MIC1Prostate differentiation factor
  • NAG-1
  • NAG-1NSAID-regulated gene 1 protein
  • NSAID (nonsteroidal inflammatory drug)-activated protein 1
  • PDF
  • PDFGDF-15
  • PLAB
  • Placental bone morphogenetic protein
  • Placental TGF-beta
  • PTGF-beta
  • PTGFBPTGF-beta


Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and -9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Publications for GDF-15 (DGD150)(80)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

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Showing Publications 1 - 10 of 80. Show All 80 Publications.
Publications using DGD150 Applications Species
S Yoshida, T Saito, K Shibagaki, K Hirao, T Yuza, N Tomosugi, H Honda Changes of biomarkers for erythropoiesis, iron metabolism, and FGF23 by supplementation with roxadustat in patients on hemodialysis Scientific Reports, 2023;13(1):3181. 2023-01-01 [PMID: 36823243] (Human) Human
M Gherghe, AM Lazar, MD Mutuleanu, CI Bordea, S Ionescu, RI Mihaila, C Petroiu, AE Stanciu Evaluating Cardiotoxicity in Breast Cancer Patients Treated with HER2 Inhibitors: Could a Combination of Radionuclide Ventriculography and Cardiac Biomarkers Predict the Cardiac Impact? Cancers, 2022;15(1):. 2022-01-01 [PMID: 36612202] (Human) Human
JS Quist, AB Klein, K Færch, K Beaulieu, M Rosenkilde, AS Gram, A Sjödin, S Torekov, B Stallknech, C Clemmensen, MB Blond Effects of acute exercise and exercise training on plasma GDF15 concentrations and associations with appetite and cardiometabolic health in individuals with overweight or obesity - A secondary analysis of a randomized controlled trial Appetite, 2022;182(0):106423. 2022-01-01 [PMID: 36563967] (Human) Human
TE Peterson, C Landon, SA Haberlen, F Bhondoekha, MW Plankey, FJ Palella, DA Piggott, JB Margolick, TT Brown, WS Post, KC Wu Circulating biomarker correlates of left atrial size and myocardial extracellular volume fraction among persons living with and without HIV BMC cardiovascular disorders, 2022;22(1):393. 2022-01-01 [PMID: 36057773] (Human) Human
L Wu, L Luo, L Zhou, N Li, X Qin GDF-15 and sST-2 act as biomarkers of disease severity but not independent predictors in idiopathic membranous nephropathy International immunopharmacology, 2022;111(0):109150. 2022-01-01 [PMID: 36027852] (Human) Human
M Sugimoto, R Suzuki, Y Nozawa, T Takagi, N Konno, H Asama, Y Sato, H Irie, J Nakamura, M Takasumi, M Hashimoto, T Kato, R Kobashi, O Suzuki, Y Hashimoto, T Hikichi, H Ohira Clinical usefulness and acceleratory effect of macrophage inhibitory cytokine-1 on biliary tract cancer: an experimental biomarker analysis Cancer Cell International, 2022;22(1):250. 2022-01-01 [PMID: 35948981] (Human) Human
J Luther, AG Vannier, EA Schaefer, RP Goodman The circulating proteomic signature of alcohol-associated liver disease JCI Insight, 2022;7(14):. 2022-01-01 [PMID: 35866482] (Human) Human
H Kared, AS Wolf, A Alirezayla, A Ravussin, G Solum, TT Tran, F Lund-Johan, JT Vaage, LS Nissen-Mey, UC Nygaard, O Hungnes, AH Robertson, LM Næss, L Trogstad, P Magnus, LA Munthe, S Mjaaland Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults Nature Communications, 2022;13(1):4165. 2022-01-01 [PMID: 35851055] (Human) Human
V Ananthapad, TC Frost, KM Soroko, A Knott, BJ Magliozzi, PC Gokhale, VG Tirunagaru, RC Doebele, JA DeCaprio Milademetan is a highly potent MDM2 inhibitor in Merkel cell carcinoma JCI Insight, 2022;7(13):. 2022-01-01 [PMID: 35801592] (Mouse) Mouse
T Arinaga-Hi, T Ide, J Akiba, H Suzuki, R Kuwahara, K Amano, T Kawaguchi, T Sano, E Inoue, H Koga, K Mitsuyama, Y Koga, T Torimura Growth differentiation factor 15 as a novel diagnostic and therapeutic marker for autoimmune hepatitis Scientific Reports, 2022;12(1):8759. 2022-01-01 [PMID: 35610317] (Human) Human
Show All 80 Publications.

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Blogs on GDF-15.

Taking Biomarker Discovery From 2D to 3D: Increased Biological Activity of EVs Isolated From 3D Prostate Cancer Cultures
Jamshed Arslan, Pharm D, PhD Tissues within the human body are made of a three-dimensional (3D) arrangement of cells working together to perform vital functions. The commonly used 2D monolayer cultures have limited ...  Read full blog post.

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Gene Symbol GDF15