Lymphotoxin beta R/TNFRSF3 Antibody Pair

Product Discontinued

Lymphotoxin beta R/TNFRSF3 Antibody Pair Summary

• Description: Quality control test: Standard curve using mammalian expressed recombinant protein as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human LTBR.
  
  
• Capture antibody: mouse monoclonal anti-LTBR (100 ug)
• Detection antibody: biotinylated mouse monoclonal anti-LTBR IgG1 Kappa (50 ug)
• Standard Curve Range: 3 ng/ml to 100 ng/ml
• Assay Type: Sandwich ELISA
• Clonality: Monoclonal
• Gene: LTBR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA 3 ng/ml - 100 ng/ml

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Lymphotoxin beta R/TNFRSF3 Antibody Pair

• CD18
• D12S370
• ltbetar
• LT-BETA-R
• LTBR
• lymphotoxin B receptor
• Lymphotoxin beta R
• lymphotoxin beta receptor (TNFR superfamily, member 3)
• Lymphotoxin-beta receptor
• LymphotoxinbR
• TNF RIII
• TNF Rrp
• TNFCRTNF-RIII
• TNFR superfamily, member 3
• TNFR2-RP
• TNFR3
• TNF-R-III
• TNFR-RP
• TNFRSF3
• TNFRSF3TNFR-III
• Tumor necrosis factor C receptor
• Tumor necrosis factor receptor 2-related protein
• tumor necrosis factor receptor superfamily member 3
• tumor necrosis factor receptor superfamily, member 3
• Tumor necrosis factor receptor type III

Background

LT-beta-R, also known as lymphotoxin beta receptor and tumor necrosis factor receptor superfamily member 3 is a 47 kD transmembrane protein containing 3 TNF receptor domains. The LT-beta-R is a receptor for the heterotrimeric lymphotoxin complex (composed of LT alpha and LT beta as well as LIGHT. LT-beta-R is highly expressed in the lung, liver, and kidney and moderately expressed expressed in the heart and testes. LT-beta-R is weakly expressed in the brain, thymus, spleen, and lymph nodes. The cytoplasmic tail of LT-beta-R interacts with TRAF3, TRAF4, and TRAF5 as well as the hepatitis C virus core protein. Ligand binding to LT-beta-R has been shown to induce apoptosis (via TRAF3 and TRAF5) and play a role in the development of lymphoid organs.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: LTBR