Ly-6G/Ly-6C Antibody (1A8) [Alexa Fluor™ Plus 555]

• Reactivity: Mu
• Clone: 1A8
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 555

Ly-6G/Ly-6C Antibody (1A8) [Alexa Fluor™ Plus 555] Summary

• Specificity: Detects mouse Ly-6G in Flow Cytometry.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Ly-6G/Ly-6C Antibody (1A8) [Alexa Fluor™ Plus 555]

• GR
• Gr1
• Gr-1
• Ly-6
• Ly6G
• Ly-6G

Background

The myeloid differentiation antigen Gr-1, also known as Ly-6G, is a member of the Ly-6 family (1). The 1A8 antibody binds to Ly-6G while the RB6‑8C5 antibody also reacts weakly with Ly-6C-transfected EL4 cells (2). Ly-6G is a 21-25 kDa glycosyolphosphatidylinositol-anchored protein that is predominatly expressed in granulocytes in bone marrow.

1. Spangrude, G.J. et al. (1988) Science 241:58.
2. Fleming, T.J. et al. (1993) J. Immunol. 151:2399.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.