LXR beta/NR1H2 Antibody

Images

 
Western Blot: LXR beta/NR1H2 Antibody [NBP1-76256] - Human lung tissue lysate with LXR-B antibody at (A) 1 and (B) 2 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

LXR beta/NR1H2 Antibody Summary

Immunogen
Antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus human LXR-B. The immunogen is located within the first 50 amino acids of LXR-B.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NR1H2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1-2 ug/ml
  • ELISA 1:100-1:2000
Control Peptide
LXR beta/NR1H2 Peptide (NBP1-76256PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for LXR beta/NR1H2 Antibody

  • Liver X receptor beta
  • LXR beta
  • LXR-b
  • NER-I
  • NERliver X receptor-beta
  • NR1H2
  • nuclear orphan receptor LXR-beta
  • Nuclear receptor NER
  • Nuclear receptor subfamily 1 group H member 2
  • nuclear receptor subfamily 1, group H, member 2
  • oxysterols receptor LXR-beta
  • RIP15
  • steroid hormone-nuclear receptor NER
  • Ubiquitously-expressed nuclear receptorLXRB
  • UNR
  • UNRLX receptor beta

Background

LXR-B belongs to the Liver X Receptor family that encodes highly homologous transcription factors. Like the highly homologous LXR-A, LXR-B forms heterodimers with the retinoic acid receptor RXRalpha, which function as sensors for cellular oxysterols which when activated, increase the expression of genes that control sterol and fatty acid metabolism and homeostasis. Recent experiments have indicated that the LXRs can also modulate both innate and adaptive immune responses. Other studies suggest that genetic variability at the LXR-B gene locus may be a risk factor for Alzheimer's disease. One hypothesis postulates that LXR may be upstream of ApoE and potentiates the risk associated effects of the epsilon3 allele.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NR1H2
Entrez
Uniprot