Loricrin Antibody - BSA Free

Immunohistochemistry-Paraffin: Loricrin Antibody [NBP2-62700] - Staining of human kidney shows no positivity in exocrine glandular cells as expected.

Immunohistochemistry-Paraffin: Loricrin Antibody [NBP2-62700] - Staining of human duodenum, kidney, prostate and skin using Anti-LOR antibody NBP2-62700 (A) shows similar protein distribution across tissues to independent antibody NBP2-62716 (B).

Immunohistochemistry-Paraffin: Loricrin Antibody [NBP2-62700] - Analysis in human skin and kidney tissues. Corresponding LOR RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: Loricrin Antibody [NBP2-62700] - Staining of human duodenum shows no positivity in glandular cells as expected.

Immunohistochemistry-Paraffin: Loricrin Antibody [NBP2-62700] - Staining of human prostate shows no positivity in glandular cells as expected.

Immunohistochemistry-Paraffin: Loricrin Antibody [NBP2-62700] - Staining of human skin shows moderate to strong positivity in epidermal cells.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Loricrin Antibody - BSA Free Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to amino acids: SGSGYVSSQQVTQTSCAPQPSYGGGSS
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LORICRIN
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Loricrin Recombinant Protein Antigen (NBP2-62700PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Protein A purified

Alternate Names for Loricrin Antibody - BSA Free

• loricrin
• LRN
• MGC111513

Background

Loricrin encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LORICRIN