LMW-PTP/ACP1 Antibody

Western Blot: LMW-PTP/ACP1 Antibody [NB100-56474] - Analysis of LMW-PTP/ACP1 antibody in the 1) absence and 2) presence of immunizing peptide in human liver lysate using this antibody at 1 ug/ml.

Product Discontinued

LMW-PTP/ACP1 Antibody Summary

• Immunogen: A portion of amino acids 50-100 of human ACP1 was used as the immunogen.
• Specificity: The amino acid sequence used as the immunogen for this antibody is 100% homologous in human, 93% in dog and orangutan, 86% in chicken and 80% homologous in mouse and rat (isoform a). It is also 100% homologous in human ACP1 isoforms c and d. An uncharacterized 45 kD band is also seen and blocked by the immunizing peptide.
• Predicted Species: Canine (93%), Primate (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ACP1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1-3 ug/ml
• Control:

  Human Liver Whole Tissue Lysate (Adult Whole Normal)
  LMW-PTP/ACP1 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS containing 0.2% gelatin
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein G purified

Alternate Names for LMW-PTP/ACP1 Antibody

• acid phosphatase 1, soluble
• acid phosphatase of erythrocyte
• ACP1
• Adipocyte acid phosphatase
• cytoplasmic phosphotyrosyl protein phosphatase
• EC 3.1.3.2
• EC 3.1.3.48
• HAAP
• LMWPTP
• LMW-PTP
• LMW-PTPase
• Low molecular weight cytosolic acid phosphatase
• low molecular weight phosphotyrosine protein phosphatase
• MGC111030
• MGC3499
• protein tyrosine phosphatase
• Red cell acid phosphatase 1

Background

Official Gene Symbol: ACP1 Gen Bank Accession Number: NP_009030 Gene ID: 52 (Human) Gene Map Locus: 2p25 (Human) ACP1 (E.C 3.1.3.2) is a unique member of Phosphotyrosine Protein phosphatase family of proteins. It is ubiquitously expressed acid phosphatase functioning as an acid phosphatase and a protein tyrosine phosphatase. ACP1 has a cysteine-based catalytic mechanism and hydrolyzes protein tyrosine phosphate to protein tyrosine and orthophosphate. Reports suggest a functional role of ACP1 in TCR signaling and control of cell-cell adhesion through regulation of cytoskeleton assembly.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACP1
• Entrez:
  • 52(Human)
• Uniprot:
  • NP_009030(Human)