LITAF Antibody (1F9)

Images

 
Western Blot: LITAF Antibody (AT1F9) [NBP1-30250] - Cell lysates of HeLa(20ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human LITAF (1:2000). Proteins were visualized using a goat ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
1F9
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

LITAF Antibody (1F9) Summary

Immunogen
Recombinant human LITAF (1-161aa) purified from E. coli
Specificity
This antibody is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human LITAF protein.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
LITAF
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:3000
  • ELISA 1:100-1:2000
Application Notes
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:2000-1:3000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4) and 10% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for LITAF Antibody (1F9)

  • CMT1C
  • FLJ38636
  • lipopolysaccharide-induced TNF factor
  • lipopolysaccharide-induced TNF-alpha factor
  • lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • LITAF
  • LPS-induced TNF-alpha factor
  • MGC116698
  • MGC116700
  • MGC125275
  • MGC125276
  • p53-induced gene 7 protein
  • PIG7
  • PIG7MGC116701
  • SIMPLE
  • SIMPLEMGC125274
  • Small integral membrane protein of lysosome/late endosome
  • TP53I7
  • tumor protein p53 inducible protein 7

Background

Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol LITAF
Entrez
Uniprot