LHR Antibody - BSA Free

Immunohistochemistry-Paraffin: LHR Antibody [NLS1436] - Anti-LHCGR / LHR / LH Receptor antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: LHR Antibody [NLS1436] - Ovary, Graafian Follicle

Immunohistochemistry-Paraffin: LHR Antibody [NLS1436] - Placenta

Immunohistochemistry-Paraffin: LHR Antibody [NLS1436] - Colon Myenteric Plexus

Immunohistochemistry-Paraffin: LHR Antibody [NLS1436] - Anti-LHCGR / LHR / LH Receptor antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: LHR Antibody [NLS1436] - Anti-hCG receptor antibody IHC of human ovary, corpus luteum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

• Reactivity: Hu, Bv, Ca, Rt, Pm, Pm
• Applications: IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

LHR Antibody - BSA Free Summary

• Immunogen: Synthetic 19 amino acid peptide from C-terminus of human LHR.
• Epitope: C-Terminus
• Localization: Secreted
• Specificity: Human LHR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Rat (95%), Primate (100%), Monkey (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LHCGR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/ml

Reactivity Notes

Bovine reactivity reported in scientific literature (Martin I et al). Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (95%), Bat (89%), Rabbit (89%), Equine (89%). Use in Canine reported in scientific publication (PMID: 32584181).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Notes

Product can be stored undiluted at 4C for up to 1 month.

Alternate Names for LHR Antibody - BSA Free

• CGR
• FLJ41504
• HHG
• hypergonadotropic hypogonadism
• LCGR
• LCGRLH/CGR
• LGR2
• LH/CG-R
• LHCGR
• LHR
• LHRHR
• LHRLGR2ULG5
• LSH-R
• Luteinizing hormone receptor
• luteinizing hormone/choriogonadotropin receptor
• lutropin/choriogonadotropin receptor
• lutropin-choriogonadotropic hormone receptor
• ULG5

Background

LHCGR has been reported in brain, cervix, epididymis, ovary, placenta, prostate, testis, umbilical cord, and uterus. ESTs have been isolated from fetal lung/testis/B-cell and testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for LHR Antibody (NLS1436)(6)

Publications using NLS1436

• Scarlet D, Aurich C, Ille N et al. Anti-Muellerian Hormone, inhibin A, gonadotropins and gonadotropin receptors in bull calves after partial scrotal resection, orchidectomy and Burdizzo castration. Theriogenology 1905-07-08 [PMID: 27693012] (IHC)
• Noci I, Sorbi F, Mannini L et al. LH/hCG-Receptor Expression May Have a Negative Prognostic Value in Low-Risk Endometrial Cancer. Front Oncol 2016-09-09 [PMID: 27610354]
• Martin I, Rodrigues MMP, Fujihara CJ et al. Localization patterns of steroid and luteinizing hormone receptors in the corpus luteum of Nelore (Bos taurus indicus) cows throughout the estrous cycle. Livestock Science. 2013-08-01 (IHC, Bovine)
• Zwida KH, Kutzler MA. Canine splenic hemangiosarcoma cells express and activate luteinizing hormone receptors in vitro Am J Vet Res 2022-11-03 [PMID: 36327166] (ICC/IF, Canine)
  
  Details:
  Citation using the FITC version of this antibody.
• Kiefel CA, Kutzler MA Assessment of luteinizing hormone receptor expression in structural support tissues of canine hip and femorotibial joints Am. J. Vet. Res. 2020-07-01 [PMID: 32584181] (IHC, Canine)
• Yung Y, Aviel-Ronen S, Maman E et al. Localization of Luteinizing Hormone Receptor Protein in the Human Ovary. Mol. Hum. Reprod. 2014-05-29 [PMID: 24874553] (IHC-P, Human)

Review for LHR Antibody (NLS1436) (1)

Average Rating: 4

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Yuval Yung ICC Human 06/22/2014

Summary

• Application: Immunocytochemistry
• Species: Human
• Lot: 7343/44AP10-1A

FAQs for LHR Antibody (NLS1436). (Showing 1 - 1 of 1 FAQs).

1. Could you please tell me the exact homology between the sequence used to generate the NLS1436 antibody and the bovine LHR amino acid sequence?
   • The immunogen, which is proprietary, is 19 amino acids long and shares 17 similar amino acids with the bovine LHR (http://www.uniprot.org/uniprot/Q28005#sequences) sequence (89%).

Bioinformatics

• Gene Symbol: LHCGR
• Entrez:
  • 3973(Human)
• Uniprot:
  • P22888(Human)