LCLAT1 Antibody

Western Blot: LCLAT1 Antibody [NBP2-19339] - Sample (20 ug of whole cell lysate) A: HeLa B: HeLa membrane, 10% SDS PAGE gel, diluted at 1:500.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

LCLAT1 Antibody Summary

• Description: Novus Biologicals Rabbit LCLAT1 Antibody (NBP2-19339) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human LCLAT1. The exact sequence is proprietary.
• Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LCLAT1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 49 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%), Porcine (87%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 1% BSA, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for LCLAT1 Antibody

• 1-acylglycerol-3-phosphate O-acyltransferase 8
• 1-AGPAT 8
• Acyl-CoA:lysocardiolipin acyltransferase 1
• AGPAT8lysocardiolipin acyltransferase
• ALCAT11AGPAT8
• EC 2.3.1.-
• EC 2.3.1.51
• FLJ37965
• HSRG1849
• LYCAT
• lysocardiolipin acyltransferase 1
• UNQ1849,1-AGP acyltransferase 8

Background

Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) andlysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipinas substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme forcardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid(PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: LCLAT1
• Uniprot:
  • Q6UWP7(Human)