Latent TGF-beta bp2/LTBP-2 Antibody [DyLight 650]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 650

Latent TGF-beta bp2/LTBP-2 Antibody [DyLight 650] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Latent TGF‑ beta bp2/LTBP‑2
  Gln36-Glu1821
  Accession # Q14767
• Specificity: Detects human Latent TGF‑ beta bp2/LTBP‑2 in direct ELISAs and Western blots. In direct ELISAs, approximately 40% cross-reactivity with recombinant mouse (rm) LTBP-2 is observed, and less than 1% cross-reactivity with recombinant human LTBP-1 and rmLTBP-4 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: LTBP2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Latent TGF-beta bp2/LTBP-2 Antibody [DyLight 650]

• C14orf141
• GLC3D
• Latent TGFbeta bp2
• Latent TGF-beta bp2
• latent transforming growth factor beta binding protein 2
• latent-transforming growth factor beta-binding protein 2
• LTBP2
• LTBP-2
• LTBP3chromosome 14 open reading frame 141
• MSTP031

Background

LTBP2, also known as latent-transforming growth factor beta-binding protein 2, is a 195 kDa, 1,821 amino acid protein that is involved in assembly and organization of cellular structure as a member of the latent transforming growth factor=beta binding protein (LTBP) family. Current research is being conducted to study the effect of the protein on diseases and disorders such as fibrosis, primary congenital glaucoma type 3D, carcinoma, hepatitis, melanoma, corneal edema, Weill-Marchesani Syndrome, and pancreatitis. The protein interacts in elastic fiber formation, paxillin interaction, mitochondrial apoptosis, extracellular matrix organization, and molecular mechanisms of cancer pathways with other proteins including FYN, FBLN5, and ABL1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LTBP2