Laminin alpha 3/Laminin-5 Antibody (546215) [Alexa Fluor® 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
546215
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 350

Order Details

Laminin alpha 3/Laminin-5 Antibody (546215) [Alexa Fluor® 350] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human Laminin alpha 3/Laminin‑5
aa 21-1713
Accession # NP_000218
Specificity
Detects human Laminin alpha 3/Laminin‑5 in direct ELISAs and Western blots. In direct ELISAs, no cross reactivity with recombinant human (rh) Laminin  alpha 1, beta 1, gamma 2, or recombinant mouse Laminin  alpha 4 is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Laminin alpha 3/Laminin-5 Antibody (546215) [Alexa Fluor® 350]

  • Epiligrin
  • LAMA3
  • Laminin alpha 3
  • Laminin5
  • Laminin-5

Background

Laminins are heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma  chains. Through interactions with integrins, dystroglycan and other receptors, laminins contribute to cell differentiation, cell shape and migration, and maintenance of tissue phenotypes and survival. Laminin alpha 3/Laminin-5, also known as epiligrin, includes alpha 3, beta 3, and gamma 2 subunits. It is abundant in transitional epithelium, stratified squamous epithelia, lung mucosa and other epithelial glands and contributes to initiation and maintenance of epithelial cell anchorage to the underlying connective tissue. Within aa 21‑1713 of the alpha 3 subunit, human and mouse share 77% amino acid sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Laminin alpha 3/Laminin-5 Antibody (IC21441U) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 IC21441U
Alexa Fluor 405 IC21441V
Alexa Fluor 488 IC21441G
Alexa Fluor 532 FAB21441X
Alexa Fluor 594 IC21441T
Alexa Fluor 647 IC21441R
Alexa Fluor 700 IC21441N
Alexa Fluor 750 IC21441S
Allophycocyanin FAB21441A
Biotin FAB21441B
DyLight 350 FAB21441D
DyLight 405 FAB21441E
DyLight 488 FAB21441K
DyLight 550 FAB21441L
DyLight 594 FAB21441M
DyLight 650 FAB21441W
DyLight 680 FAB21441Y
DyLight 755 FAB21441Z
FITC FAB21441F
HRP FAB21441H
Janelia Fluor 549 FAB21441I
Janelia Fluor 646 FAB21441J
PE FAB21441P
PerCP FAB21441C

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