KMT1A/SUV39H1 Antibody - BSA Free

Western Blot: KMT1A/SUV39H1 Antibody [NBP3-03367] - Western blot analysis of extracts of various cell lines, using KMT1A/SUV39H1 antibody (NBP3-03367) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

KMT1A/SUV39H1 Antibody - BSA Free Summary

• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human KMT1A/SUV39H1 (NP_003164.1). MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIY
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SUV39H1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500 - 1:1000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for KMT1A/SUV39H1 Antibody - BSA Free

• EC 2.1.1.355
• H3-K9-HMTase 1
• Histone H3-K9 methyltransferase 1
• histone-lysine N-methyltransferase SUV39H1
• histone-lysine N-methyltransferase, H3 lysine-9 specific 1
• KMT1A
• KMT1A/SUV39H1
• KMT1AEC 2.1.1.43
• Lysine N-methyltransferase 1A
• MG44
• Position-effect variegation 3-9 homolog
• Su(var)3-9 homolog 1
• suppressor of variegation 3-9 (Drosophila) homolog 1
• suppressor of variegation 3-9 homolog 1 (Drosophila)
• Suppressor of variegation 3-9 homolog 1
• Suppressor of variegation 3-9 homolog 1, Suvar) 3-9 homolog
• SUV39H
• SUV39H1

Background

SUV39H1 (suppressor of variegation 3-9 homolog 1) is a histone methyltransferase that specifically trimethylates histone H3 at lys 9. Trimethylation stimulates the binding of heterochromatin proteins (HPs) which leads to epigenetic transcriptional repression in heterochromatin regions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Bioinformatics

• Gene Symbol: SUV39H1