Recombinant Human KISS1 Protein

SDS-Page: Recombinant Human KISS1 Protein [NBC1-18516] - KISS1, 12.6 kDa (120 aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE

• Reactivity: Hu
• Applications: PAGE
• Concentration: 1 mg/ml

Recombinant Human KISS1 Protein Summary

• Description: An un-tagged recombinant protein corresponding to the amino acids 1-120 of Human KISS1
  
  

  Source: E.coli

  Amino Acid Sequence: MEPLEKVASV GNSRPTGQQL ESLGLLAPGE QSLPCTERKP AATARLSRRG TSLSPPPESS GSPQQPGLSA PHSRQIPAPQ GAVLVQREKD LPNYNWNSFG LRFGKREAAP GNHGRSAGRG

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: KISS1
• Purity: >90%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 12.6 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 10% glycerol
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human KISS1 Protein

• KiSS-1 metastasis-suppressor
• KiSS1
• KiSS-1
• kisspeptin
• Kisspeptin-1
• malignant melanoma metastasis-suppressor
• metastasis-suppressor KiSS-1
• Metastin
• MGC39258

Background

KiSS-1 metastasis-suppressor (KISS1) is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. Expression of KiSS1 has been localized to specific regions of the hypothalamus in many species and is regulated by gonadal steroids and across the estrous cycle. Recombinant KISS1 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

FAQs for KISS1 Recombinant Protein (NBC1-18516). (Showing 1 - 1 of 1 FAQ).

1. I am interested in buying NBC1-18516. Have you tested it as a biologically active molecule to trigger cellular pathway?
   • At this time, we have only tested this protein for use in ELISA and PAGE. We would not be able to recommend this protein to trigger cellular pathways.

Bioinformatics

• Gene Symbol: KISS1