Species: Hu
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Rt
Applications: WB
Host: Rabbit Polyclonal
Species: Rt
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
KISS1 gene encodes metastin, also known as kisspeptin or KiSS-1 peptide, which binds to a G protein-coupled receptor GPR54. KISS1 is dominantly expressed in brain (e.g. anteroventral periventricular nucleus, AVPV arcuate nucleus, ARC), placenta, and pancreas, etc. Metastin plays an important role in regulating the GnRH secretion in brain and MMP-9 expression in placenta, which is associated with development of puberty and sex maturation (e.g. Idiopathic hypogonadotropic hypogonadism, IHH) as well as placentation (e.g. pre-eclampsia), respectively. Metastin was originally discovered as a tumor metastasis suppressor (e.g. melanoma, breast cancer).
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Mouse
|
| Product By Gene ID |
3814 |
| Alternate Names |
- KiSS-1 metastasis-suppressor
- KiSS-1
- kisspeptin
- Kisspeptin-1
- kisspeptin-1
- malignant melanoma metastasis-suppressor
- metastasis-suppressor KiSS-1
- METASTIN
- MGC39258
|
Research Areas for KISS1
Find related products by research area and learn more about each of the different research areas below.
CancerPhospho-Specific
