KISS1 Antibody

Western Blot: KISS1 Antibody [H00003814-B01P] - Analysis of KISS1 expression in transfected 293T cell line by KISS1 polyclonal antibody. Lane 1: KISS1 transfected lysate(14.70 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

KISS1 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: KISS1 (NP_002247.3, 1 a.a. - 138 a.a.) full-length human protein. MNSLVSWQLLLFLCATHFGEPLEKVASVGNSRPTGQQLESLGLLAPGEQSLPCTERKPAATARLSRRGTSLSPPPESSGSPQQPGLSAPHSRQIPAPQGAVLVQREKDLPNYNWNSFGLRFGKREAAPGNHGRSAGRG
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: KISS1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: It has been used for WB and Functional.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for KISS1 Antibody

• KiSS-1 metastasis-suppressor
• KiSS1
• KiSS-1
• kisspeptin
• Kisspeptin-1
• malignant melanoma metastasis-suppressor
• metastasis-suppressor KiSS-1
• Metastin
• MGC39258

Background

KISS1 gene encodes metastin, also known as kisspeptin or KiSS-1 peptide, which binds to a G protein-coupled receptor GPR54. KISS1 is dominantly expressed in brain (e.g. anteroventral periventricular nucleus, AVPV arcuate nucleus, ARC), placenta, and pancreas, etc. Metastin plays an important role in regulating the GnRH secretion in brain and MMP-9 expression in placenta, which is associated with development of puberty and sex maturation (e.g. Idiopathic hypogonadotropic hypogonadism, IHH) as well as placentation (e.g. pre-eclampsia), respectively. Metastin was originally discovered as a tumor metastasis suppressor (e.g. melanoma, breast cancer).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KISS1
• Uniprot:
  • NP_002247.3(Human)