KISS1 Antibody Pair

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Summary
Product Discontinued
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    • Catalog Number
      H00003814-AP42
    • Availability
      Product Discontinued

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KISS1 Antibody Pair Summary

Description
Quality control test: Standard curve using recombinant protein (H00003814-P01) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human KISS1.

  • Capture antibody: mouse monoclonal anti-KISS1 IgG2a Kappa (100 ug)
  • Detection antibody: biotinylated mouse monoclonal anti-KISS1 IgG2a Kappa (50 ug)
  • Standard Curve Range
    0.3 ng/ml to 100 ng/ml
    Assay Type
    Sandwich ELISA
    Clonality
    Monoclonal
    Gene
    KISS1
    Purity
    Immunogen affinity purified

    Applications/Dilutions

    Dilutions
    • Sandwich ELISA 0.3 ng/ml - 100 ng/ml

    Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    1x PBS, pH 7.4
    Preservative
    No Preservative
    Purity
    Immunogen affinity purified

    Notes

    This product is produced by and distributed for Abnova, a company based in Taiwan.

    Alternate Names for KISS1 Antibody Pair

    • KiSS-1 metastasis-suppressor
    • KiSS1
    • KiSS-1
    • kisspeptin
    • Kisspeptin-1
    • malignant melanoma metastasis-suppressor
    • metastasis-suppressor KiSS-1
    • Metastin
    • MGC39258

    Background

    KISS1 gene encodes metastin, also known as kisspeptin or KiSS-1 peptide, which binds to a G protein-coupled receptor GPR54. KISS1 is dominantly expressed in brain (e.g. anteroventral periventricular nucleus, AVPV arcuate nucleus, ARC), placenta, and pancreas, etc. Metastin plays an important role in regulating the GnRH secretion in brain and MMP-9 expression in placenta, which is associated with development of puberty and sex maturation (e.g. Idiopathic hypogonadotropic hypogonadism, IHH) as well as placentation (e.g. pre-eclampsia), respectively. Metastin was originally discovered as a tumor metastasis suppressor (e.g. melanoma, breast cancer).

    Limitations

    This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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    Bioinformatics

    Gene Symbol KISS1