KCNK3 Antibody (S374-48) [Alexa Fluor™ Plus 594]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF, IHC
• Clone: S374-48
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 594

KCNK3 Antibody (S374-48) [Alexa Fluor™ Plus 594] Summary

• Immunogen: Fusion protein amino acids 251-411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1. Mouse: 96% identity (156/161 amino acids identical). Human: 76% identity (163/161 amino acids identical). <30% identity with TASK3.
• Localization: Membrane
• Specificity: Less then 30% identity with TASK3.Detects approx 50kDa. Does not cross-react with TASK3.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: KCNK3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for KCNK3 Antibody (S374-48) [Alexa Fluor™ Plus 594]

• Acid-sensitive potassium channel protein TASK-1
• cardiac potassium channel
• K2p3.1
• KCNK3
• OAT1
• potassium channel subfamily K member 3
• potassium channel, subfamily K, member 3
• potassium inwardly-rectifying channel, subfamily K, member 3
• TASK
• TASK1
• TASK-1
• TASKacid-sensitive potassium channel protein TASK
• TBAK1
• TWIK-related acid-sensitive K(+) channel 1
• TWIK-related acid-sensitive K+ channel
• two P domain potassium channel
• Two pore K(+) channel KT3.1
• Two pore potassium channel KT3.1

Background

The KCNK3 gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNK3