KCNK3 Antibody (S374-48) [Alexa Fluor® 750]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF, IHC
• Clone: S374-48
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

KCNK3 Antibody (S374-48) [Alexa Fluor® 750] Summary

• Immunogen: Fusion protein amino acids 251-411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1. Mouse: 96% identity (156/161 amino acids identical). Human: 76% identity (163/161 amino acids identical). <30% identity with TASK3.
• Localization: Membrane
• Specificity: Less then 30% identity with TASK3.Detects approx 50kDa. Does not cross-react with TASK3.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: KCNK3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for KCNK3 Antibody (S374-48) [Alexa Fluor® 750]

• Acid-sensitive potassium channel protein TASK-1
• cardiac potassium channel
• K2p3.1
• KCNK3
• OAT1
• potassium channel subfamily K member 3
• potassium channel, subfamily K, member 3
• potassium inwardly-rectifying channel, subfamily K, member 3
• TASK
• TASK1
• TASK-1
• TASKacid-sensitive potassium channel protein TASK
• TBAK1
• TWIK-related acid-sensitive K(+) channel 1
• TWIK-related acid-sensitive K+ channel
• two P domain potassium channel
• Two pore K(+) channel KT3.1
• Two pore potassium channel KT3.1

Background

The KCNK3 gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNK3