KCNK12 Antibody [Alexa Fluor™ Plus 555]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 555

KCNK12 Antibody [Alexa Fluor™ Plus 555] Summary

• Immunogen: KCNK12 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human KCNK12. The immunogen is located within amino acids 320 - 370 of KCNK12. Amino Acid Squence: PGSRLRRRLAALGA
• Specificity: KCNK12 antibody is predicted to not cross-react with other KCNK protein family members.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KCNK12
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for KCNK12 Antibody [Alexa Fluor™ Plus 555]

• potassium channel subfamily K member 12
• potassium channel, subfamily K, member 12
• tandem pore domain potassium channel THIK-2
• THIK2
• THIK-2
• THIK-2THIK2Tandem pore domain halothane-inhibited potassium channel 2

Background

KCNK12 is a gene which codes for a protein that functions as a potassium channel subunit that most likely needs to associate with another protein subunit in order to properly create a potassium channel and consists of 430 amino acids and weighs approximately 47 kDa. Current studies are being done on diseases and disorders relating to this gene including generalized epilepsy, migranes, vitiligo, pancreatitis, and neuronitis. KCNK12 has also been shown to have importance in pathways such as the cholera infection, hepatic ABC transporter, PKA signaling, and sweet taste signaling pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNK12