KCNK12 Antibody [Alexa Fluor® 647]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 647

KCNK12 Antibody [Alexa Fluor® 647] Summary

• Immunogen: KCNK12 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human KCNK12. The immunogen is located within amino acids 320 - 370 of KCNK12. Amino Acid Squence: PGSRLRRRLAALGA
• Specificity: KCNK12 antibody is predicted to not cross-react with other KCNK protein family members.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KCNK12
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for KCNK12 Antibody [Alexa Fluor® 647]

• potassium channel subfamily K member 12
• potassium channel, subfamily K, member 12
• tandem pore domain potassium channel THIK-2
• THIK2
• THIK-2
• THIK-2THIK2Tandem pore domain halothane-inhibited potassium channel 2

Background

KCNK12 is a gene which codes for a protein that functions as a potassium channel subunit that most likely needs to associate with another protein subunit in order to properly create a potassium channel and consists of 430 amino acids and weighs approximately 47 kDa. Current studies are being done on diseases and disorders relating to this gene including generalized epilepsy, migranes, vitiligo, pancreatitis, and neuronitis. KCNK12 has also been shown to have importance in pathways such as the cholera infection, hepatic ABC transporter, PKA signaling, and sweet taste signaling pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNK12