Jak1 [p Tyr1022] Antibody


Western Blot: JAK1 [p Tyr1022] Antibody [NB100-82005] - Analysis of extracts from HT29 cells untreated or treated with UV using JAK1 [p Tyr1022] antibody.
Immunohistochemistry: JAK1 [p Tyr1022] Antibody [NB100-82005] - Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using JAK1 (phospho-Tyr1022) antibody
Western Blot: JAK1 [p Tyr1022] Antibody [NB100-82005] - Analysis of extract from thyroid cancer cell line BHP cells (BHP 5, 14, 15 and 17), using JAK1 (phospho-Tyr1022) antibody. Only BHP 5, 15 and 17 can detect the ...read more

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IHC-P
1.0 mg/ml

Order Details

Jak1 [p Tyr1022] Antibody Summary

The antiserum was produced against synthesized phosphopeptide derived from human JAK1 around the phosphorylation site of tyrosine 1022 (K-E-YP-Y-T).
p Tyr1022
JAK1 (specific to Phospho-Tyr1022) detects endogenous levels of JAK1 only when phosphorylated at tyrosine 1022.
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, and 50% glycerol.
0.02% Sodium Azide
1.0 mg/ml
Immunogen affinity purified


Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
130 kDa

Alternate Names for Jak1 [p Tyr1022] Antibody

  • EC 2.7.10
  • JAK-1
  • JAK1Atyrosine-protein kinase JAK1
  • JAK1B
  • Janus kinase 1EC
  • JTK3


Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterised by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. It is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon recpeptor complexes. These kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signalling proteins and a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

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Contact Information

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Gene Symbol JAK1

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