Jagged 1 Antibody - BSA Free

Analysis in human placenta and lymph node tissues using NBP1-90208 antibody. Corresponding JAG1 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: Jagged 1 Antibody [NBP1-90208] - Staining of human placenta shows moderate membranous positivity in trophoblastic cells.

Immunohistochemistry-Paraffin: Jagged 1 Antibody [NBP1-90208] - Staining of human lymph node shows no cytoplasmic positivity in non-germinal center cells as expected.

Immunohistochemistry-Paraffin: Jagged 1 Antibody [NBP1-90208] - Staining of human duodenum shows moderate cytoplasmic and membranous positivity in glandular cells.

Immunohistochemistry-Paraffin: Jagged 1 Antibody [NBP1-90208] - Staining of human skin shows weak cytoplasmic positivity in squamous epithelial cells.

• Reactivity: Hu, Mu, Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Jagged 1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Jagged 1 Antibody - BSA Free (NBP1-90208) is a polyclonal antibody validated for use in IHC. Anti-Jagged 1 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: LRKRRKPGSHTHSASEDNTTNNVREQLNQIKNPIEKHGANTVPIKDYENKNSKMSKIRTHNSEVEEDDMDKHQQKARFAKQPAYTLVDREEKPPNGTPTKHPNWTNKQDNRDLESAQSLNRMEYI
• Predicted Species: Mouse (94%), Rat (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: JAG1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Jagged 1 Recombinant Protein Antigen (NBP1-90208PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Jagged 1 Antibody - BSA Free

• AGS
• AHDMGC104644
• Alagille syndrome
• AWS
• CD339 antigen
• CD339
• HJ1
• JAG1
• Jagged 1
• Jagged1
• JAGL1
• protein jagged-1

Background

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is theligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations thatalter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play arole in hematopoiesis. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Jagged 1 Antibody (NBP1-90208)(2)

Publications using NBP1-90208

• Georgia Nikoloudaki, Eirini-Iouliani Basdeki, Nikolaos P. Kerezoudis, Konstantinos I. Tosios Notch-1/2 receptors and Jagged-1 ligand, but not HERP-1 transcription factor, are immunohistochemically expressed in the epithelial lining of periapical cysts Journal of Clinical and Experimental Dentistry 2024-01-01 [PMID: 38314334]
• Gunin AG, Petrov VV, Golubtzova NN et al. Age-related changes in angiogenesis in human dermis. Exp. Gerontol. 2014-04-24 [PMID: 24768823] (IHC-P, Human)

Bioinformatics

• Gene Symbol: JAG1