IRF9 Antibody (SR1836) - BSA Free

Western Blot: IRF9 Antibody (SR1836) [NBP3-22016] - Western blot analysis using NBP3-22016 in Jurkat cell lysate.

• Reactivity: Hu
• Applications: WB, Flow, ICC/IF
• Clone: SR1836
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

IRF9 Antibody (SR1836) - BSA Free Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human IRF9 (Uniprot #: Q00978).
• Specificity: Detects endogenous levels of total IRF9
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: IRF9
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:50
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Western Blot 1:1000-1:5000
• Theoretical MW: 48 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for IRF9 Antibody (SR1836) - BSA Free

• IFN-alpha-responsive transcription factor subunit
• interferon regulatory factor 9
• Interferon-stimulated gene factor 3 gamma
• interferon-stimulated transcription factor 3, gamma (48kD)
• interferon-stimulated transcription factor 3, gamma 48kDa
• IRF9
• IRF-9
• ISGF3 p48 subunit
• ISGF3
• ISGF3G
• ISGF3GISGF-3 gamma
• p48
• Transcriptional regulator ISGF3 subunit gamma

Background

Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IRF9