WB: Approx. 60 kDa band observed in human ovary lysates (calculated MW of 53.1 kDa band according to NP_006138.1). In transfected HEK293 transiently expressing IRF6 a band of approx. 55 kDa is observed. This band is not observed in the non-transfected HEK293. IHC-P: Human kidney shows strong nuclear staining in DCT and glomerulus.
Read Publications using NBP1-51911 in the following applications:
Mouse reactivity reported in scientific literature (PMID: 25358290).
Alternate Names for IRF6 Antibody
interferon regulatory factor 6
Van der Woude syndrome
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.