integrin beta 4 binding protein Antibody

Images

 
Western Blot: integrin beta 4 binding protein Antibody [NBP1-52641] - Affinity purified rabbit anti-eIF6 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. eIF6 was also ...read more
Immunohistochemistry: integrin beta 4 binding protein Antibody [NBP1-52641] - Samples: FFPE serial sections of human ovarian carcinoma. Antibody: Affinity purified rabbit anti- eIF6 used at a dilution of 1:1,000 ...read more
Immunohistochemistry: integrin beta 4 binding protein Antibody [NBP1-52641] - Samples: FFPE serial sections of mouse renal cell carcinoma. Antibody: Affinity purified rabbit anti- eIF6 used at a dilution of 1:1,000 ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml
 

Independent Antibodies

 

Biological Strategies

     

Order Details

integrin beta 4 binding protein Antibody Summary

Immunogen
The immunogen for this product maps to a region between residue 150 and 200 of human Eukaryotic Translation Initiation Factor 6 using the numbering given in entry NP_852133.1 (GeneID 3692).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EIF6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunohistochemistry
  • Immunoprecipitation 2-5 mcg/mg

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for integrin beta 4 binding protein Antibody

  • B(2)GCN homolog
  • b(2)gcn
  • B4 integrin interactor
  • CAB
  • EIF3Ap27(BBP)
  • eIF-6
  • eukaryotic translation initiation factor 3A
  • eukaryotic translation initiation factor 6
  • ITGB4BPintegrin beta 4 binding protein
  • p27 beta-4 integrin-binding protein
  • p27BBP

Background

Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding two different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol EIF6