Integrin beta 3/CD61 Antibody (909114) [Alexa Fluor® 594]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
909114
Clonality
Monoclonal
Host
Rat
Conjugate
Alexa Fluor 594
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Integrin beta 3/CD61 Antibody (909114) [Alexa Fluor® 594] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin alpha 2b and Integrin beta 3 linked heterodimer
Leu32-Arg988 (Integrin alpha 2b) & Glu26-Asp717 (Integrin beta 3)
Accession # NP_034705 (Integrin alpha 2b) & O54890 (Integrin beta 3)
Specificity
Detects mouse Integrin  beta 3/CD61 in direct ELISA.
Isotype
IgG1
Clonality
Monoclonal
Host
Rat
Gene
ITGB3
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin beta 3/CD61 Antibody (909114) [Alexa Fluor® 594]

  • CD61 antigen
  • CD61
  • GP3A
  • GP3Aplatelet glycoprotein IIIa
  • GPIIIA
  • GPIIIaintegrin beta-3
  • INGRB3
  • Integrin beta 3
  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • ITG B3
  • ITGB3
  • Platelet membrane glycoprotein IIIa

Background

Integrin beta 3 (ITGB3) is also known as platelet glycoprotein IIIa (GPIIIa) and CD61. Integrins are integral cell-surface proteins known to participate in both cell adhesion and cell-surface mediated signaling. They are composed of an alpha chain and a beta chain. ITGB3 is an integrin beta chain that forms a heterodimer with alpha-IIb or alpha-V chains. It is involved in platelet aggregation, and serves as an anchor for fibrinogen, allowing platelets to form aggregates or clots. A functional absense of ITGB3 leads to Glanzmann's thrombasthenia, a condition where platelets are activated, but fail to form an aggregate. Alternatively spliced transcripts encoding different proteins have been described, in human.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Integrin beta 3/CD61 Antibody (FAB41182T) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB41182U
Alexa Fluor 405 FAB41182V
Alexa Fluor 488 FAB41182G
Alexa Fluor 594 FAB41182T
Alexa Fluor 647 FAB41182R
Alexa Fluor 700 FAB41182N
Alexa Fluor 750 FAB41182S

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