Integrin beta 2/CD18 Antibody (WT.3) [FITC] Summary
Membrane; single pass type I membrane protein.
NB100-65305 reacts with the rat beta 2 integrin, which is designated CD18. The beta 2 integrin may be associated with the integrin alphaL, alphaX or alphaM subunits. CD18 is expressed by all leucocytes. Clone WT.3 has been shown to inhibit homotypic aggregation of PHA blasts. It also blocks binding of rat lymphocytes to purified rat ICAM-1.
Protein G purified
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Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
FITC (A=495, E=519)
PBS and 1.0% BSA
0.09% Sodium Azide
Protein G purified
- Flow Cytometry 1:10-1:1000
Alternate Names for Integrin beta 2/CD18 Antibody (WT.3) [FITC]
- 959 beta subunit precursor)10
- CD18 antigen
- CD18beta 2
- cell surface adhesion glycoprotein (LFA-1
- integrin beta-2
- integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1;macrophage antigen 1 (mac-1) beta subunit)
- integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
- leukocyte cell adhesion molecule CD18
- leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C
- LFA-1 beta
- MAC-1 beta
- p150,95 beta
CD18 is an integrin. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA1, and combines with the alpha M chain to form the integrin Mac1. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling. CD18 is expressed by most leucocytes. Defects in the CD18 gene result in leukocyte adhesion deficiency.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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