Integrin beta 2/CD18 Products

Description

CD18 is an integrin. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA1, and combines with the alpha M chain to form the integrin Mac1. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling. CD18 is expressed by most leucocytes. Defects in the CD18 gene result in leukocyte adhesion deficiency.

Bioinformatics

Entrez	16414 Mouse 309684 Rat 3689 Human
Uniprot	AAH05861 Human AAH05861.1 Human NM_000211 Human NP_001120963 Human P05107 Human
Product By Gene ID	3689
Alternate Names	959 beta subunit precursor)10 CD18 antigen CD18beta 2 cell surface adhesion glycoprotein (LFA-1 CR3 integrin beta-2 integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1;macrophage antigen 1 (mac-1) beta subunit) integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) LAD LCAMB leukocyte cell adhesion molecule CD18 leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C MF17 MFI7 P150

Research Areas for Integrin beta 2/CD18

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
CD Markers
Cytokine Research
Immunology
Phospho-Specific

Related Integrin beta 2/CD18 Blog Posts

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CD11b/CD18 and Neutrophil-Epithelial Interactions as Targets for Anti-Inflammatory Therapies The beta-2 integrins, a family of four cell surface transmembrane glycoproteins expressed only on leukocytes, include CD11a/CD18, CD11b/CD18, CD11c/CD18, and CD11d/CD18. They consist of a common beta subunit (CD18) and homologous alpha subunits (CD11a...    Read more.

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