Integrin alpha 5/CD49e Antibody (238307) [Allophycocyanin]

K562 human chronic myelogenous leukemia cell line was stained with Mouse Anti-Human Integrin a5/CD49e APC-conjugated Monoclonal Antibody (Catalog # FAB1864A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Hu
• Applications: Flow
• Clone: 238307
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

Integrin alpha 5/CD49e Antibody (238307) [Allophycocyanin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Integrin alpha 5/CD49e
  Phe42-Tyr995
  Accession # P08648
• Specificity: Detects human Integrin alpha 5/CD49e.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ITGA5
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin alpha 5/CD49e Antibody (238307) [Allophycocyanin]

• CD49 antigen-like family member E
• CD49e antigen
• CD49e
• Fibronectin receptor subunit alpha
• fibronectin receptor, alpha subunit
• FNRAVLA5A
• Integrin alpha 5
• integrin alpha-5
• Integrin alpha-F
• integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
• ITGA5
• very late activation protein 5, alpha subunit
• VLA-5 alpha
• VLA-5

Background

The Integrin alpha 5 subunit, also known as CD49e, associates with the Integrin beta 1 subunit (CD29) to form the VLA-5 complex. It functions as a receptor for fibronectin and is expressed on fibroblasts, endothelial cells, epithelial cells, platelets and some melanoma cell lines (1, 2).

1. Springer, T.A. et al. (1982) Immunol. Rev. 68:171.
2. Te Velde, A. et al. (1988) J. Immunol. 140:1548.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ITGA5
• Uniprot:
  • P08648()