Integrin alpha 5/CD49e Products

Description

CD49e is a type I integral membrane glycoprotein, known as alpha5 integrin, VLA-5 alpha chain. It forms noncovalent heterodimer with integrin beta1 (CD29). CD49e contains two disulfide-linked subunits of 135 kDa and 24 kDa, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells. CD49e/CD29 complex binds to fibronection and neural adhesion molecule L1. It mediates monocytes migration, involves in the regulation of cells survival and apoptosis, and co-stimulates T cell activation.

Bioinformatics

Product By Gene ID	3678
Alternate Names	CD49 antigen-like family member E CD49e antigen CD49e Fibronectin receptor subunit alpha fibronectin receptor, alpha subunit FNRAVLA5A Integrin alpha 5 integrin alpha-5 Integrin alpha-F integrin, alpha 5 (fibronectin receptor, alpha polypeptide) ITGA5 very late activation protein 5, alpha subunit VLA-5 alpha VLA-5

Research Areas for Integrin alpha 5/CD49e

Find related products by research area and learn more about each of the different research areas below.

CD Markers
Cell Biology
Cytoskeleton Markers
GPCR
Immunology
Signal Transduction