Integrin alpha 2b/CD41 Antibody (PM6/248) [DyLight 488]

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Product Details

Summary
Reactivity Hu, Bb, MdSpecies Glossary
Applications Flow
Clone
PM6/248
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Integrin alpha 2b/CD41 Antibody (PM6/248) [DyLight 488] Summary

Immunogen
Human platelet plasma membrane
Specificity
NB100-63779 recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone PM6/248 recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ITGA2B
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry

Reactivity Notes

Reacts with Human. Cross reacts with Baboon, Mink and Mustelid.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Integrin alpha 2b/CD41 Antibody (PM6/248) [DyLight 488]

  • CD41 antigen
  • CD41
  • CD41BHPA3
  • GP2B
  • GP2Bintegrin alpha-IIb
  • GPalpha IIb
  • GPIIb
  • GTA
  • HPA3
  • Integrin alpha 2b
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41)
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B)
  • ITGA2b
  • ITGAB
  • platelet fibrinogen receptor, alpha subunit
  • Platelet membrane glycoprotein IIb
  • platelet-specific antigen BAK

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB100-63779APC
DyLight 350 Labeled NB100-63779UV
DyLight 405 Labeled NB100-63779V
DyLight 680 Labeled NB100-63779FR
DyLight 755 Labeled NB100-63779IR
FITC Labeled NB100-63782
PE Labeled NB100-63779PE
PerCP Labeled NB100-63779PCP

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Bioinformatics

Gene Symbol ITGA2B
Entrez