INSIG-1 Antibody [DyLight 650]


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Product Details

Reactivity Hu, RtSpecies Glossary
Applications WB
Please see the vial label for concentration. If unlisted please contact technical services.

INSIG-1 Antibody [DyLight 650] Summary

A synthetic peptide representing an internal region of the human INSIG-1 protein (between residues 1-100) according to Swiss-Prot# O15503.
ER Membrane
This is specific for Insig1 but not Insig2.
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 650
DyLight 650 (A=652, E=672)
50mM Sodium Borate
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified


Application Notes
This INSIG-1 antibody is useful for Immunocytochemistry/Immunofluorescence and Western Blot, where a band is seen at ~30 kDa representing the Insig1 protein. In ICC/IF positive staining was localized to the ER membrane in HepG2 cells.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
30 kDa

Reactivity Notes

Human and rat.

Alternate Names for INSIG-1 Antibody [DyLight 650]

  • CL6
  • CL-6
  • INSIG-1 membrane protein
  • INSIG-1
  • insulin induced gene 1
  • insulin-induced gene 1 protein
  • MGC1405


Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Biotin Labeled NB110-55244B
DyLight 488 Labeled NB110-55244G
DyLight 550 Labeled NB110-55244R
HRP Labeled NB110-55244H

Additional INSIG-1 Antibody [DyLight 650] Products

INSIG-1 NB110-55244C

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Blogs on INSIG-1

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Contact Information

Product PDFs


Gene Symbol INSIG1

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