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INSIG-1 Products

Antibodies
INSIG-1 Antibody - BSA Free
INSIG-1 Antibody - BSA Free
NB110-55244
Western Blot INSIG-1 Antibody - BSA Free
Immunocytochemistry/ Immunofluorescence INSIG-1 Antibody - BSA Free
Western Blot INSIG-1 Antibody - BSA Free
Species: Hu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 NB110-55244AF350
Alexa Fluor 405 NB110-55244AF405
Alexa Fluor 488 NB110-55244AF488
Alexa Fluor 532 NB110-55244AF532
Alexa Fluor 594 NB110-55244AF594
Alexa Fluor 647 NB110-55244AF647
Alexa Fluor 700 NB110-55244AF700
Alexa Fluor 750 NB110-55244AF750
Alexa Fluor Plus 405 NB110-55244AFP405
Alexa Fluor Plus 488 NB110-55244AFP488
Alexa Fluor Plus 555 NB110-55244AFP555
Alexa Fluor Plus 594 NB110-55244AFP594
Alexa Fluor Plus 647 NB110-55244AFP647
Alexa Fluor Plus 680 NB110-55244AFP680
Allophycocyanin NB110-55244APC
Biotin NB110-55244B
CoraFluor 1 NB110-55244CL1
DyLight 350 NB110-55244UV
DyLight 405 NB110-55244V
DyLight 488 NB110-55244G
DyLight 550 NB110-55244R
DyLight 594 NB110-55244DL594
DyLight 650 NB110-55244C
DyLight 680 NB110-55244FR
DyLight 755 NB110-55244IR
FITC NB110-55244F
HRP NB110-55244H
Janelia Fluor 525 NB110-55244JF525
Janelia Fluor 549 NB110-55244JF549
Janelia Fluor 646 NB110-55244JF646
Janelia Fluor 669 NB110-55244JF669
PE NB110-55244PE
PerCP NB110-55244PCP
mFluor Violet 450 SE NB110-55244MFV450
mFluor Violet 500 SE NB110-55244MFV500
mFluor Violet 610 SE NB110-55244MFV610
Formulation Catalog # Availability Price  
BSA Free NB110-55244SS
INSIG-1 Antibody - BSA Free
INSIG-1 Antibody - BSA Free
NBP2-84095
Western Blot INSIG-1 Antibody - BSA Free
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
BSA Free NBP2-84095-0.1ml
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We have 2 INSIG-1 Antibodies
Lysates
INSIG-1 Overexpression Lysate ...
INSIG-1 Overexpression Lysate
NBP2-04727
Western Blot INSIG-1 Overexpression Lysate
Species: Hu
Applications: WB
INSIG-1 Overexpression Lysate ...
INSIG-1 Overexpression Lysate
NBL1-12003
Western Blot INSIG-1 Overexpression Lysate
Species: Hu
Applications: WB
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We have 2 INSIG-1 Lysates
Proteins
INSIG-1 Antibody Blocking Pep ...
INSIG-1 Antibody Blocking Peptide
NB110-55244PEP
Applications: AC
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We have 1 INSIG-1 Protein

Description

Insig1 is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells.

Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. Insig1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Bioinformatics

Product By Gene ID 3638
Alternate Names
  • CL6
  • CL-6
  • INSIG-1 membrane protein
  • INSIG-1
  • insulin induced gene 1
  • insulin-induced gene 1 protein
  • MGC1405

Research Areas for INSIG-1

Find related products by research area and learn more about each of the different research areas below.

Cholesterol Metabolism
ER Markers
Lipid and Metabolism
Signal Transduction