ILT2/CD85j/LILRB1 Antibody (3D3-1D12)

Images

 
Western Blot: ILT2/CD85j/LILRB1 Antibody (3D3-1D12) [H00010859-M01] - LILRB1 monoclonal antibody (M01), clone 3D3-1D12 Analysis of LILRB1 expression in SW-13.
Sandwich ELISA: ILT2/CD85j/LILRB1 Antibody (3D3-1D12) [H00010859-M01] - Detection limit for recombinant GST tagged LILRB1 is approximately 0.1ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
3D3-1D12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

ILT2/CD85j/LILRB1 Antibody (3D3-1D12) Summary

Immunogen
LILRB1 (AAH15731, 1 a.a. ~ 523 a.a) full length recombinant protein with GST tag.MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINKVFCNKASIRIPWTKLKTHPICLSLDKVIMEMSTCEEPRSPNGPSPIATASGQSEYGFAEKVVEGISVSVNSIVIRIGAKAFNASFELSQLRIYSVNAHWEHGDLRFTRIQDPQRGEVLTFKEINWQMIRIEADATQSSHLEIMCAPVRLITNQSKIRVTLKRRLKDCNVIATKLVLILDDLLWVLTDSQLKAMVQ
Specificity
LILRB1 - leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
LILRB1
Purity
IgG purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ILT2/CD85j/LILRB1 Antibody (3D3-1D12)

  • CD85 antigen-like family member J
  • CD85j antigen
  • CD85j
  • Ig-like transcript 2
  • ILT2
  • ILT-2
  • ILT2FLJ37515
  • Immunoglobulin-like transcript 2
  • leukocyte Ig-like receptor-1
  • Leukocyte immunoglobulin-like receptor 1
  • leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform
  • leukocyte immunoglobulin-like receptor subfamily B member 1
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains)
  • LILRB1
  • LIR1
  • LIR1LIR-1MIR-7CD85MIR7CD85 antigen
  • member 1
  • MIR7
  • Monocyte/macrophage immunoglobulin-like receptor 7

Background

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol LILRB1
Entrez
OMIM
Uniprot