ILT11/LILRA5 Antibody (711828) [Alexa Fluor® 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
711828
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 405
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

ILT11/LILRA5 Antibody (711828) [Alexa Fluor® 405] Summary

Immunogen
 Chinese hamster ovary cell line CHO-derived recombinant human LILRA5/CD85f
Gly42-Arg268
Accession # A6NI73
Specificity
Detects human LILRA5/CD85f in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse ILT11/LILRA5, recombinant rat (rr) ILT11/LILRA5, rrLILRC2, recombinant human (rh) ILT4/CD85d, rhILT5/CD85a, or rhILT3/CD85k is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
LILRA5
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ILT11/LILRA5 Antibody (711828) [Alexa Fluor® 405]

  • CD85 antigen-like family member F
  • CD85
  • CD85f antigen
  • CD85f
  • ILT11
  • ILT-11
  • ILT11CD85f
  • Immunoglobulin-like transcript 11
  • leukocyte Ig-like receptor 9
  • Leukocyte immunoglobulin-like receptor 9
  • leukocyte immunoglobulin-like receptor subfamily A member 5 soluble
  • leukocyte immunoglobulin-like receptor subfamily A member 5
  • leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains)
  • LILRA5
  • LILRB7
  • LIR9
  • LIR-9
  • LIR9immunoglobulin-like transcript 11 protein
  • member 7

Background

ILT11 (also leukocyte immunoglobulin-like receptor 9 (LIR-9), CD85f, and LILRA5) is a 39-40 kDa Group 2 member of the LILR family of innate immune receptors.  It is expressed on monocytes and perhaps neutrophils, and its activation results in the secretion of proinflammatory cytokines such as TNF-a and IL-1b.  Mature human ILT11 is a 258 amino acid (aa) type I transmembrane glycoprotein.  It has a 227 aa extracellular domain (aa 42-268) that contains two C2-type Ig-like domains (aa 51‑136 and 142-230), and a 10 aa cytoplasmic tail.  ILT11 has three potential splice forms.  One is a 35 kDa soluble form of the molecule described above that shows a 27 aa substitution for aa 239-299.  The other two splice forms are analogous to the above membrane and soluble forms, but demonstrate signal sequence cleavage further downstream after Ala51.  Over aa 41-268, human ILT11 shares 58% aa identity with mouse ILT11.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol LILRA5
Uniprot