IL18R1 Antibody Pair [HRP] Summary
Description |
Solid Phase sandwich ELISA for the quantitative determination of Human IL18R1. |
Specificity |
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Human IL18R1. |
Standard Curve Range |
7.81-500 pg/ml (example only; lot dependent) |
Sensitivity |
7.8 pg/ml (example only; lot dependent) |
Assay Type |
Sandwich ELISA |
Sample Volume |
100 ul |
Gene |
IL18R1 |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Storage of components varies. See protocol for specific instructions. |
Kit Components
Components
|
- Mouse Monoclonal Detection Antibody (HRP-conjugated)
- Standard
|
Alternate Names for IL18R1 Antibody Pair [HRP]
Background
IL-18 receptor is composed of an alpha and a beta subunit that combine to form a high affinity receptor for IL-18. IL-18 receptor alpha chain, also known as CDw218a, is a 75-80 kD type I transmembrane protein. It is expressed on NK cells, neutrophils, endothelial cells, and subsets of T and B cells. The expression of CDw218a on lymphocytes is upregulated after activation. The interaction of IL-18 and IL-18 receptor has been reported to be implicated in promotion of Th1 cytokine production and atherogenesis. The H44 antibody is specific for IL-18 receptor alpha chain and has been reported to block IL-18 binding to the receptor and to be useful for the identification of IL-18 receptor by flow cytometry and IHC.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are
guaranteed for 6 months from date of receipt.
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