Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, Flow
Host: Rabbit Monoclonal
Species: Hu
Applications: WB, IHC, B/N
Host: Mouse Monoclonal
Species: Mu
Applications: ELISA
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Host: Monoclonal
Species: Hu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
IL-18 receptor is composed of an alpha and a beta subunit that combine to form a high affinity receptor for IL-18. IL-18 receptor alpha chain, also known as CDw218a, is a 75-80 kD type I transmembrane protein. It is expressed on NK cells, neutrophils, endothelial cells, and subsets of T and B cells. The expression of CDw218a on lymphocytes is upregulated after activation. The interaction of IL-18 and IL-18 receptor has been reported to be implicated in promotion of Th1 cytokine production and atherogenesis. The H44 antibody is specific for IL-18 receptor alpha chain and has been reported to block IL-18 binding to the receptor and to be useful for the identification of IL-18 receptor by flow cytometry and IHC.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human |
Product By Gene ID |
8809 |
Alternate Names |
- CD218 antigen-like family member A
- CD218a antigen
- CD218a
- CDw218a
- cytokine receptor
- IL-18R1
- IL-18R-1
- IL1R-rp
- IL1RRPIL1 receptor-related protein
- IL-1RrpIL18RA
- interleukin 18 receptor 1
- interleukin-18 receptor 1
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