IL-33 Antibody (6H496)


Western Blot: IL33 Antibody (6H496) [NBP2-30103] - Analysis of IL-33 using IL-33 monoclonal antibody in A. HUVEC cell lysate at 10 ug/ml and B. partial recombinant IL-33 (amino acids 112-270) at 1 ug/ml. Goat anti-mouse more
Simple Western: IL-33 Antibody (6H496) [NBP2-30103] - Simple Western lane view shows a specific band for IL-33 in 0.5 mg/ml of Jurkat lysate. This experiment was performed under reducing conditions using the 12-230 kDa more

Product Details

Reactivity HuSpecies Glossary
Applications WB, Simple Western
0.5 mg/ml

Order Details

IL-33 Antibody (6H496) Summary

A partial recombinant human IL-33 (amino acids 112-270) protein was used as immunogen for this antibody.
IgG1 Kappa
Protein G purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
PBS with 0.05% BSA
0.05% Sodium Azide
0.5 mg/ml
Protein G purified


  • Western Blot 1-10 ug/ml
  • Simple Western 1:50
Application Notes
In Simple Western only 10-15 uL of the recommended dilution is used per data point.

Reactivity Notes


Alternate Names for IL-33 Antibody (6H496)

  • C9orf26
  • C9orf26chromosome 9 open reading frame 26 (NF-HEV)
  • DKFZp586H0523
  • DVS27
  • DVS27-related protein
  • IL1F11
  • IL-1F11
  • IL33
  • IL-33
  • interleukin 33
  • Interleukin-1 family member 11
  • interleukin-33
  • NF-HEV
  • Nuclear factor from high endothelial venules
  • RP11-575C20.2


IL-33 is a 270 amino acid highly divergent protein belonging to the IL-1 family with an IL-1-like C-terminal domain. It is a dual function protein that may function both as a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties. IL-33 binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6. IL-33 activates NF-kappaB and MAP kinases, and drives production of TH2-associated cytokines from in vitro polarized TH2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs. It is proteolytically converted to a mature form by CASP1 and is highly expressed in high endothelial venules found in tonsils, Peyer's patches and mesenteric lymph nodes and is almost undetectable in placenta.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


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Blogs on IL-33.

Interleukin 33 (IL-33) - A dual function cytokine
IL-33 is a member of the interleukin family of cytokines that regulates a wide variety of cellular functions. Its receptor is ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and the IL-1R accessory...  Read full blog post.

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Product PDFs


Gene Symbol IL33

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