Reactivity | HuSpecies Glossary |
Applications | WB, ICC/IF |
Clone | 373802 |
Clonality | Monoclonal |
Host | Rat |
Conjugate | Alexa Fluor 647 |
Immunogen | E. coli-derived recombinant human IL‑32α Phe3-Lys131 Accession # NP_001012651 |
Specificity | Detects the alpha isoform of IL-32 in direct ELISAs. In direct ELISAs, less than 15% cross-reactivity with recombinant human (rh) IL-32 beta and rhIL‑32 gamma is observed. |
Isotype | IgG2a |
Clonality | Monoclonal |
Host | Rat |
Purity Statement | Protein A or G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Storage | Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied |
Buffer | Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide |
IL-32 alpha is the shortest and most abundant of four potential splice variants of the proinflammatory cytokine IL-32 (previously called NK4) with a predicted unmodified size of 15 kDa. Potential modifications include myristoylation and N-glycosylation. Transfected IL-32 alpha was more likely to be cell-associated as compared to IL-32 beta , suggesting an intracellular function. IL-32 is induced by mitogens in peripheral lymphocytes, by IFN‑ gamma in epithelial cells, or by IL-12 with IL-18 in NK cells and in turn Induces cytokine expression. No ortholog has been found in mouse.
Secondary Antibodies |
Isotype Controls |
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