IL-31 Recombinant Protein


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Product Details

Reactivity HuSpecies Glossary

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IL-31 Recombinant Protein Summary

A recombinant protein corresponding to Human IL-31

Source: E. coli

E. coli

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
From 20 mM phosphate buffer, 150 mM NaCl, pH 7.4 Centrifuge the vial prior to opening.
Reconstitution Instructions
Reconstitute with sterilized water to a final concentration greater than or equal to 0.1 mg/ml.


After reconstituted, dilute further with other aqueous solutions.

Alternate Names for IL-31 Recombinant Protein

  • IL31
  • IL-31interleukin-31
  • interleukin 31


IL-31 produced by activated Th2-type T cells, cooperates with a heterodimeric receptor consisting of IL-31 Receptor Anatagonist and Onconstatin-M Receptor that is constitutively expressed on epithelial cells and keratinocytes. IL-31 plays a role in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma. IL-31 is involved in the itching sensation and endorses the scratching behavior in NC/Nga mice with atopic dermatitis. IL-31 expression is connected with CLA(+) T cells and contributes to the development of atopic dermatitis-induced skin inflammation and pruritus. IL-31 is a powerful inducer of proinflammatory mediators in human colonic SEMFs. IL-31 takes part as a proinflammatory cytokine derived from Th2 cells. Serum IL-31 level is higher in patients with atopic dermatitis. IL-31 is involved in a broad range of immune- & non-immune cells & possesses potential pleiotropic physiological functions, including regulating hematopoiesis & immune response, causing inflammatory bowel disease, airway hypersensitivity & dermatitis. IL-31 human recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 141 amino acids (24-164 a.a.) and having a molecular mass of 15.8 kDa.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Contact Information

Product PDFs


Gene Symbol IL31

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