IL-21R Antibody (DMC225) - Chimeric

• Reactivity: Hu
• Applications: ELISA, Flow
• Clone: DMC225
• Clonality: Monoclonal
• Host: Human
• Conjugate: Unconjugated
• Concentration: LYOPH

IL-21R Antibody (DMC225) - Chimeric Summary

• Description: This product is shipped at ambient temperature. Store at -20C to -80C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80C (Avoid repeated freezing and thawing).
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: IL-21R recombinant protein expressed in mammalian cells (Accession# Q9HBE5). The exact amino acid sequence is proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: IL21R
• Purity: Antigen Affinity-purified from cell culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA 1:5000-10000
  • Flow Cytometry 1:100

Packaging, Storage & Formulations

• Storage: Store at -20C in powder form. Store at -80C once reconstituted.
• Buffer: PBS, pH 7.4, 5-8% Trehalose
• Preservative: Trehalose
• Concentration: LYOPH
• Purity: Antigen Affinity-purified from cell culture supernatant
• Reconstitution Instructions: Dissolve the lyophilized antibody in sterile and low endotoxin water. The recommend volume of water is lot specific. Please refer to the instructions printed on the product vial or contact technical support.

Alternate Names for IL-21R Antibody (DMC225) - Chimeric

• CD360 antigen
• CD360
• IL-21 R
• IL-21 receptor
• IL21R
• IL-21R
• interleukin 21 receptor
• interleukin-21 receptor
• MGC10967
• NILR
• Novel interleukin receptor

Background

IL21 Receptor is a novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. Both IL-21R and the gc are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL21R